Caspase 7 (Q21131812)

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mammalian protein found in Homo sapiens

CMH-1
ICE-LAP3
caspase 7, apoptosis-related cysteine peptidase
apoptotic protease MCH-3
ICE-like apoptotic protease 3
caspase-7
CASP7
caspase 7, apoptosis-related cysteine protease

Language	Label	Description	Also known as
English	Caspase 7	mammalian protein found in Homo sapiens	CMH-1 ICE-LAP3 caspase 7, apoptosis-related cysteine peptidase apoptotic protease MCH-3 ICE-like apoptotic protease 3 caspase-7 CASP7 caspase 7, apoptosis-related cysteine protease

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

cysteine-type peptidase activity

determination method

protein binding

determination method

7 references

8 April 2019

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Structural Basis of Caspase Inhibition by XIAP

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Structural basis of caspase-7 inhibition by XIAP

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

cysteine-type endopeptidase activity involved in execution phase of apoptosis

determination method

1 reference

8 April 2019

Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

cysteine-type endopeptidase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

determination method

1 reference

8 April 2019

Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

determination method

3 references

8 April 2019

ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

biological process

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

cellular response to staurosporine

determination method

1 reference

8 April 2019

Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

execution phase of apoptosis

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

apoptotic process

determination method

3 references

5 June 2018

Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55210&geneProductId=UniProtKB:P55210

determination method

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55210&geneProductId=UniProtKB:P55210

determination method

5 June 2018

Identification of novel regulators of apoptosis using a high-throughput cell-based screen.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P55210&geneProductId=UniProtKB:P55210

determination method

apoptotic process

determination method

4 references

8 April 2019

Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Identification of novel regulators of apoptosis using a high-throughput cell-based screen.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55210

determination method

physically interacts with

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL197672

Identifiers

MeSH descriptor ID

subject named as

Caspase 7

0 references

D08.811.277.656.262.500.126.350.700

0 references

D08.811.277.656.300.200.126.350.700

0 references

D12.776.476.075.405.350.700

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000298701

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000298701

ENSP00000358321

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358321

ENSP00000358324

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358324

ENSP00000358337

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358337

ENSP00000398107

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398107

ENSP00000478285

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000478285

ENSP00000478999

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000478999

ENSP00000480584

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000480584

ENSP00000358327

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358327

ENSP00000400094

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400094

ENSP00000500735

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000500735

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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