Dynein light chain LC8-type 1 (Q21132100)

http://www.ebi.ac.uk/interpro/protein/P63167

Dynein light chain, type 1/2

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63167

Dynein light chain, type 1/2, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein domain specific binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

protein C-terminus binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

14 references

8 April 2019

Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Functional regulation of oestrogen receptor pathway by the dynein light chain 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

ATM substrate Chk2-interacting Zn2+ finger (ASCIZ) Is a bi-functional transcriptional activator and feedback sensor in the regulation of dynein light chain (DYNLL1) expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa. New insights into the specificity of thioredoxin function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Network organization of the human autophagy system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Structural models of DYNLL1 with interacting partners: African swine fever virus protein p54 and postsynaptic scaffolding protein gephyrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

RACK1 and CIS mediate the degradation of BimEL in cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

cytoskeletal motor activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

cytoskeletal protein binding

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

plus-end-directed microtubule motor activity

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

dynein light intermediate chain binding

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

nitric-oxide synthase regulator activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

protein homodimerization activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

protein heterodimerization activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

scaffold protein binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

dynein intermediate chain binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Functional regulation of oestrogen receptor pathway by the dynein light chain 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

microtubule associated complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

1 reference

8 April 2019

Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

cytoplasmic dynein complex

IDA

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

26 September 2017

Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

tertiary granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

ficolin-1-rich granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

cytoplasmic dynein complex

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 January 2018

Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

cytoplasmic dynein complex

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

regulation of transcription, DNA-templated

HDA

biological process

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

substantia nigra development

1 reference

26 September 2017

Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

antigen processing and presentation of exogenous peptide antigen via MHC class II

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

endoplasmic reticulum to Golgi vesicle-mediated transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

microtubule-based process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

intraciliary retrograde transport

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

negative regulation of phosphorylation

1 reference

8 April 2019

Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

intraciliary transport involved in cilium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

neutrophil degranulation

1 reference

8 April 2019

motile cilium assembly

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

ciliary basal body-plasma membrane docking

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

positive regulation of non-motile cilium assembly

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

transport along microtubule

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

sister chromatid cohesion

IBA

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

regulation of G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63167&geneProductId=UniProtKB:P63167

spermatid development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

substantia nigra development

1 reference

8 April 2019

Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

positive regulation of insulin secretion involved in cellular response to glucose stimulus

HEP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63167

Dynein light chain, type 1/2, conserved site

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63167

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016