Azurocidin 1 (Q21132154)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

azurocidin
AZU1
neutrophil azurocidin
HBP
hHBP
heparin-binding protein
cationic antimicrobial protein 37
cationic antimicrobial protein CAP37
AZU1 protein, human

Language	Label	Description	Also known as
English	Azurocidin 1	mammalian protein found in Homo sapiens	azurocidin AZU1 neutrophil azurocidin HBP hHBP heparin-binding protein cationic antimicrobial protein 37 cationic antimicrobial protein CAP37 AZU1 protein, human

Statements

1 reference

13 November 2019

UniProt protein ID

peptidase S1A, chymotrypsin family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20160

Peptidase S1, PA clan

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20160

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase activity

determination method

1 reference

8 April 2019

Neutrophil-derived azurocidin cleaves insulin-like growth factor-binding protein-1, -2 and -4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

protein binding

determination method

1 reference

8 April 2019

Basic residues in azurocidin/HBP contribute to both heparin binding and antimicrobial activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

heparan sulfate proteoglycan binding

determination method

1 reference

8 April 2019

Neutrophil-derived heparin-binding protein (HBP/CAP37) deposited on endothelium enhances monocyte arrest under flow conditions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

toxic substance binding

determination method

1 reference

8 April 2019

Characterization of the biosynthesis, processing, and sorting of human HBP/CAP37/azurocidin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

serine-type endopeptidase activity

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20160&geneProductId=UniProtKB:P20160

determination method

serine-type endopeptidase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

azurophil granule

determination method

1 reference

26 September 2017

Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20160&geneProductId=UniProtKB:P20160

determination method

azurophil granule membrane

determination method

1 reference

8 April 2019

Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

extrinsic component of membrane

determination method

1 reference

8 April 2019

Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

extracellular space

determination method

azurophil granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

azurophil granule

determination method

biological process

positive regulation of MHC class II biosynthetic process

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

positive regulation of phagocytosis

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

negative regulation of apoptotic process

determination method

1 reference

8 April 2019

Heparin-binding protein targeted to mitochondrial compartments protects endothelial cells from apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

protein kinase C signaling

determination method

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

microglial cell activation

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

induction of positive chemotaxis

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

monocyte activation

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

regulation of vascular permeability

determination method

1 reference

8 April 2019

Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

macrophage chemotaxis

determination method

1 reference

8 April 2019

Cloning of the cDNA for the serine protease homolog CAP37/azurocidin, a microbicidal and chemotactic protein from human granulocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

protein kinase C-activating G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

defense response to bacterium

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

positive regulation of peptidyl-threonine phosphorylation

determination method

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

neutrophil-mediated killing of bacterium

determination method

1 reference

8 April 2019

Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

defense response to Gram-negative bacterium

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

cell chemotaxis

determination method

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

cellular extravasation

determination method

1 reference

8 April 2019

Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

inflammatory response

determination method

1 reference

8 April 2019

Heparin binding protein (CAP37) differentially modulates endotoxin-induced cytokine production

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

calcium-mediated signaling using intracellular calcium source

determination method

1 reference

8 April 2019

Neutrophil-derived heparin-binding protein (HBP/CAP37) deposited on endothelium enhances monocyte arrest under flow conditions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

glial cell migration

determination method

1 reference

8 April 2019

Activation of microglia: a neuroinflammatory role for CAP37

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

positive regulation of cell adhesion

determination method

positive regulation of protein kinase activity

determination method

1 reference

8 April 2019

CAP37 activation of PKC promotes human corneal epithelial cell chemotaxis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20160

determination method

serine proteases, trypsin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20160

Identifiers

MeSH descriptor ID

subject named as

AZU1 protein, human

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000233997

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000233997

ENSP00000479183

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000479183

ENSP00000481172

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481172

ENSP00000488091

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000488091

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21132154&oldid=2023016779"