Electron transfer flavoprotein subunit alpha (Q21132231)

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mammalian protein found in Homo sapiens

alpha-ETF
epididymis secretory sperm binding protein
glutaric aciduria II
electron transfer flavoprotein alpha subunit
ETFA
electron transfer flavoprotein, alpha polypeptide
electron transfer flavoprotein subunit alpha, mitochondrial

Language	Label	Description	Also known as
English	Electron transfer flavoprotein subunit alpha	mammalian protein found in Homo sapiens	alpha-ETF epididymis secretory sperm binding protein glutaric aciduria II electron transfer flavoprotein alpha subunit ETFA electron transfer flavoprotein, alpha polypeptide electron transfer flavoprotein subunit alpha, mitochondrial

Statements

1 reference

13 November 2019

UniProt protein ID

Electron transfer flavoprotein alpha subunit/FixB

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

DHS-like NAD/FAD-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

Electron transfer flavoprotein, alpha subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Electron transfer flavoprotein, alpha/beta-subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Electron transfer flavoprotein, alpha subunit, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Electron transfer flavoprotein subunit alpha, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

electron transfer activity

determination method

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

oxidoreductase activity

determination method

flavin adenine dinucleotide binding

determination method

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

Expression and characterization of two pathogenic mutations in human electron transfer flavoprotein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

protein binding

determination method

4 references

8 April 2019

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

electron transfer activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

oxidoreductase activity

determination method

3 references

8 April 2019

The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Expression and characterization of two pathogenic mutations in human electron transfer flavoprotein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

flavin adenine dinucleotide binding

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

The intraflavin hydrogen bond in human electron transfer flavoprotein modulates redox potentials and may participate in electron transfer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Expression and characterization of two pathogenic mutations in human electron transfer flavoprotein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

mitochondrial matrix

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

extracellular exosome

determination method

1 reference

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

determination method

5 references

26 September 2017

Molecular cloning and nucleotide sequence of cDNAs encoding the alpha-subunit of human electron transfer flavoprotein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

determination method

5 references

8 April 2019

Molecular cloning and nucleotide sequence of cDNAs encoding the alpha-subunit of human electron transfer flavoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

8 April 2019

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

biological process

respiratory electron transport chain

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13804

determination method

fatty acid beta-oxidation using acyl-CoA dehydrogenase

determination method

1 reference

26 September 2017

Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

electron transport chain

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13804&geneProductId=UniProtKB:P13804

determination method

fatty acid beta-oxidation using acyl-CoA dehydrogenase

determination method

physically interacts with

determination method

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

Electron transfer flavoprotein, alpha subunit, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

Electron transfer flavoprotein, alpha/beta-subunit, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

Electron transfer flavoprotein subunit alpha, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

Electron transfer flavoprotein, alpha subunit, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P13804

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000399273

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399273

ENSP00000452762

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452762

ENSP00000267950

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000267950

ENSP00000452659

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452659

ENSP00000452777

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452777

ENSP00000452942

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452942

ENSP00000453017

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453017

ENSP00000453098

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453098

ENSP00000453345

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453345

ENSP00000453422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453422

ENSP00000453753

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453753

ENSP00000454194

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454194

ENSP00000458001

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458001

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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