MYC associated factor X (Q21132757)

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mammalian protein found in Homo sapiens
  • class D basic helix-loop-helix protein 4
  • MAX
  • protein max
  • bHLHd4
  • Myc-associated factor X
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Language Label Description Also known as
English
MYC associated factor X
mammalian protein found in Homo sapiens
  • class D basic helix-loop-helix protein 4
  • MAX
  • protein max
  • bHLHd4
  • Myc-associated factor X

Statements

molecular function
protein binding
determination method
IPI
24 references
retrieved
8 April 2019
stated in
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation
GOA
curator
UniProt
UniProt protein ID
P61244
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Nmi protein interacts with regions that differ between MycN and Myc and is localized in the cytoplasm of neuroblastoma cells in contrast to nuclear MycN
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Sirt1 deacetylates c-Myc and promotes c-Myc/Max association
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Sin3b interacts with Myc and decreases Myc levels
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Drugging MYCN through an allosteric transition in Aurora kinase A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Targeting of Miz-1 is essential for Myc-mediated apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
A human MAP kinase interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic profiling of Myc-associated proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61244
determination method
IPI
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
IBA
IDA
5 references
retrieved
10 September 2018
stated in
Functional and in silico assessment of MAX variants of unknown significance
GOA
curator
UniProt
UniProt protein ID
P61244
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P61244&geneProductId=UniProtKB:P61244
determination method
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P61244&geneProductId=UniProtKB:P61244
determination method
IBA
retrieved
7 November 2018
stated in
Functional and in silico assessment of MAX variants of unknown significance
GOA
curator
UniProt
UniProt protein ID
P61244
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P61244&geneProductId=UniProtKB:P61244
determination method
IDA
retrieved
7 November 2018
stated in
Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P61244&geneProductId=UniProtKB:P61244
determination method
IDA
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P61244&geneProductId=UniProtKB:P61244
determination method
IBA
cell component
biological process

Identifiers

Ensembl protein ID
 
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