General transcription factor IIA subunit 1 (Q21133391)

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mammalian protein found in Homo sapiens

general transcription factor IIA, 1, 19/37kDa
TFIIA-42
transcription initiation factor IIA subunit 1
TFIIAL
TFIIA alpha, p55
transcription initiation factor TFIIA 42 kDa subunit
GTF2A1
glucose regulated protein, 58kD pseudogene
TFIIA alpha/beta subunits
general transcription factor IIA 1

Language	Label	Description	Also known as
English	General transcription factor IIA subunit 1	mammalian protein found in Homo sapiens	general transcription factor IIA, 1, 19/37kDa TFIIA-42 transcription initiation factor IIA subunit 1 TFIIAL TFIIA alpha, p55 transcription initiation factor TFIIA 42 kDa subunit GTF2A1 glucose regulated protein, 58kD pseudogene TFIIA alpha/beta subunits general transcription factor IIA 1

Statements

1 reference

13 November 2019

UniProt protein ID

Transcription factor IIA, alpha/beta subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P52655

Transcription factor IIA, beta-barrel

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P52655

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

TBP-class protein binding

determination method

1 reference

8 April 2019

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

determination method

1 reference

8 April 2019

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription coactivator activity

determination method

1 reference

8 April 2019

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription factor binding

determination method

1 reference

8 April 2019

Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

protein binding

determination method

4 references

8 April 2019

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Activity of the upstream TATA-less promoter of the p21(Waf1/Cip1) gene depends on transcription factor IIA (TFIIA) in addition to TFIIA-reactive TBP-like protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

protein heterodimerization activity

determination method

1 reference

8 April 2019

Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

RNA polymerase II general transcription initiation factor activity

determination method

1 reference

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription factor TFIIA complex

determination method

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

5 June 2018

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription factor TFIID complex

determination method

1 reference

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription factor TFIIA complex

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

transcription by RNA polymerase II

determination method

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

5 June 2018

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

5 June 2018

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52655&geneProductId=UniProtKB:P52655

determination method

snRNA transcription by RNA polymerase II

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

positive regulation of nucleic acid-templated transcription

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

transcription by RNA polymerase II

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Near-atomic resolution visualization of human transcription promoter opening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52655

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000409492

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000409492

ENSP00000452454

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452454

ENSP00000298173

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000298173

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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