Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization (Q21133881)

17 August 2022

3

Cilla Söderhäll

Cilla

Söderhäll

1 reference

17 August 2022

7

Raija

Sormunen

Raija Sormunen

1 reference

17 August 2022

Mari H Tervaniemi

1

Mari H

Tervaniemi

1 reference

17 August 2022

H Annika Siitonen

2

H Annika

Siitonen

1 reference

17 August 2022

Gurinder Minhas

4

Gurinder

Minhas

1 reference

17 August 2022

Jyrki Vuola

5

Jyrki

Vuola

1 reference

17 August 2022

Inkeri Tiala

6

Inkeri

Tiala

1 reference

17 August 2022

Lena Samuelsson

8

Lena

Samuelsson

1 reference

17 August 2022

Sari Suomela

9

Sari

Suomela

1 reference

17 August 2022

Outi Elomaa

11

Outi

Elomaa

1 reference

Creative Commons Attribution 4.0 International

17 August 2022

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

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volume

7

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issue

11

0 references

page(s)

e49920

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copyright license

start time

26 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic β-cells

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RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product

19 March 2017

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Analysis of the coding sequence and expression of the coiled-coil α-helical rod protein 1 gene in normal and neoplastic epithelial cervical cells

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Vimentin intermediate filaments modulate the motility of mitochondria

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Immune synapses: mitochondrial morphology matters

12 September 2017

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The eEF1γ subunit contacts RNA polymerase II and binds vimentin promoter region

12 September 2017

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Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.

12 September 2017

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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin

12 September 2017

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Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

12 September 2017

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Evidence for altered Wnt signaling in psoriatic skin.

12 September 2017

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Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

12 September 2017

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Cytokinetic abscission: cellular dynamics at the midbody

12 September 2017

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Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin

12 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

CCHCR1 is up-regulated in skin cancer and associated with EGFR expression

12 September 2017

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12 September 2017

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12 September 2017

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The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice

12 September 2017

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Impact of Stat3 activation upon skin biology: a dichotomy of its role between homeostasis and diseases

12 September 2017

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12 September 2017

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Desmoplakin: an unexpected regulator of microtubule organization in the epidermis

12 September 2017

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The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes

12 September 2017

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Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

12 September 2017

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12 September 2017

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The centrosome in human genetic disease

12 September 2017

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Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

12 September 2017

1 reference

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Transgenic mouse models support HCR as an effector gene in the PSORS1 locus

12 September 2017

1 reference

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HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

The 3' untranslated region of human vimentin mRNA interacts with protein complexes containing eEF-1gamma and HAX-1

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Keratins (Kl6 and Kl7) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Inhibition of keratin 17 expression with antisense and RNAi strategies: exploring novel therapy for psoriasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Microtubule-Targeted Chemotherapeutic Agents Inhibit Signal Transducer and Activator of Transcription 3 (STAT3) Signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Keratin down-regulation in vimentin-positive cancer cells is reversible by vimentin RNA interference, which inhibits growth and motility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

A novel role of phospho-beta-catenin in microtubule regrowth at centrosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

The role of heparin-binding EGF-like growth factor and amphiregulin in the epidermal proliferation of psoriasis in cooperation with TNFalpha

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Altered expression of angiogenesis and lymphangiogenesis markers in the uninvolved skin of plaque-type psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Vimentin expression influences flow dependent VASP phosphorylation and regulates cell migration and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells--transcriptional activation and messenger RNA stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Stat3 activity is required for centrosome duplication in chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Candidate housekeeping genes require evaluation before their selection for studies of human epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049920

Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: possible involvement of the rho signal cascade.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506594

Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes

29 November 2018

1 reference

12 December 2020

Increased nuclear beta-catenin in suprabasal involved psoriatic epidermis

1 reference

12 December 2020

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

1 reference

12 December 2020

Keratin 17: a useful marker in anti-psoriatic therapies

1 reference

12 December 2020

The roles of calmodulin, actin, and vimentin in steroid synthesis by adrenal cells

1 reference

12 December 2020

Altered keratin 17 peptide ligands inhibit in vitro proliferation of keratinocytes and T cells isolated from patients with psoriasis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0049920

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