Serine palmitoyltransferase long chain base subunit 1 (Q21135688)

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mammalian protein found in Homo sapiens

SPT1
SPTLC1
LCB 1
long chain base biosynthesis protein 1
serine palmitoyltransferase 1
serine-palmitoyl-CoA transferase 1
serine C-palmitoyltransferase
SPT 1

Language	Label	Description	Also known as
English	Serine palmitoyltransferase long chain base subunit 1	mammalian protein found in Homo sapiens	SPT1 SPTLC1 LCB 1 long chain base biosynthesis protein 1 serine palmitoyltransferase 1 serine-palmitoyl-CoA transferase 1 serine C-palmitoyltransferase SPT 1

Statements

1 reference

13 November 2019

UniProt protein ID

Pyridoxal phosphate-dependent transferase, major domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15269

Pyridoxal phosphate-dependent transferase domain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15269

Pyridoxal phosphate-dependent transferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15269

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Aminotransferase, class I/classII, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

serine C-palmitoyltransferase activity

determination method

6 references

8 April 2019

Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Autophagy regulates sphingolipid levels in the liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

acyltransferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

protein binding

determination method

4 references

8 April 2019

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Orm family proteins mediate sphingolipid homeostasis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Orm family proteins mediate sphingolipid homeostasis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

pyridoxal phosphate binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

catalytic activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

serine C-palmitoyltransferase complex

determination method

1 reference

8 April 2019

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

endoplasmic reticulum membrane

determination method

biological process

sphingolipid metabolic process

determination method

3 references

8 April 2019

Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

sphinganine biosynthetic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

sphingosine biosynthetic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

sphingomyelin biosynthetic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

positive regulation of lipophagy

determination method

1 reference

8 April 2019

Autophagy regulates sphingolipid levels in the liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

lipid metabolism

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

sphingolipid biosynthetic process

determination method

3 references

8 April 2019

Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

8 April 2019

Autophagy regulates sphingolipid levels in the liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15269

determination method

Aminotransferase, class I/classII

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15269

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000262554

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000262554

ENSP00000337635

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000337635

ENSP00000495388

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000495388

ENSP00000493933

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000493933

ENSP00000496627

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496627

ENSP00000495764

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000495764

ENSP00000494770

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494770

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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