Fructose-bisphosphatase 1 (Q21154612)

http://www.ebi.ac.uk/interpro/protein/P09467

Fructose-1-6-bisphosphatase class I, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fructose-1,6-bisphosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

6 references

8 April 2019

cDNA sequence and kinetic properties of human lung fructose(1, 6)bisphosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

phosphoric ester hydrolase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

identical protein binding

5 references

8 April 2019

A human protein-protein interaction network: a resource for annotating the proteome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

monosaccharide binding

1 reference

8 April 2019

3 references

8 April 2019

cDNA sequence and kinetic properties of human lung fructose(1, 6)bisphosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

fructose 1,6-bisphosphate 1-phosphatase activity

9 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

fructose 1,6-bisphosphate 1-phosphatase activity

10 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

fructose 1,6-bisphosphate 1-phosphatase activity

9 references

8 April 2019

Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

1 reference

31 October 2017

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

1 reference

8 April 2019

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

fructose metabolic process

IMP

biological process

1 reference

31 October 2017

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

fructose 6-phosphate metabolic process

TAS

2 references

31 October 2017

Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

cellular response to magnesium ion

1 reference

8 April 2019

cDNA sequence and kinetic properties of human lung fructose(1, 6)bisphosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

3 references

8 April 2019

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

regulation of gluconeogenesis

1 reference

8 April 2019

Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

negative regulation of cell growth

IMP

1 reference

8 April 2019

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

protein homotetramerization

negative regulation of Ras protein signal transduction

1 reference

8 April 2019

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

5 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09467&geneProductId=UniProtKB:P09467

sucrose biosynthetic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

fructose 1,6-bisphosphate metabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

fructose metabolic process

IMP

fructose 6-phosphate metabolic process

TAS

3 references

8 April 2019

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09467

Fructose-1-6-bisphosphatase class I, N-terminal

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09467

Fructose-1,6-bisphosphatase, active site

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09467

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016