Death associated protein kinase 1 (Q21155668)

Protein kinase-like domain superfamily

1 reference

Death-like domain superfamily

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Ankyrin repeat-containing domain superfamily

1 reference

Ankyrin repeat-containing domain, protein family

1 reference

Death domain, protein family

1 reference

Roc domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Ankyrin repeat, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

11 references

8 April 2019

An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Programmed cell death 6 (PDCD6) protein interacts with death-associated protein kinase 1 (DAPk1): additive effect on apoptosis via caspase-3 dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

identical protein binding

IPI

3 references

8 April 2019

GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

calmodulin-dependent protein kinase activity

IPI

1 reference

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

protein serine/threonine kinase activity

3 references

16 July 2018

The death-associated protein kinases: structure, function, and beyond

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

16 July 2018

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

protein kinase activity

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

protein serine/threonine kinase activity

4 references

8 April 2019

The death-associated protein kinases: structure, function, and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

regulation of apoptotic process

IBA

biological process

1 reference

8 April 2019

The death-associated protein kinases: structure, function, and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

negative regulation of translation

TAS

1 reference

8 April 2019

DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

negative regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

Programmed cell death 6 (PDCD6) protein interacts with death-associated protein kinase 1 (DAPk1): additive effect on apoptosis via caspase-3 dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

The death-associated protein kinases: structure, function, and beyond

regulation of autophagy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

TAS

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53355&geneProductId=UniProtKB:P53355

apoptotic signaling pathway

1 reference

8 April 2019

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

protein autophosphorylation

IMP

3 references

8 April 2019

The death-associated protein kinases: structure, function, and beyond

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

regulation of translation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

extrinsic apoptotic signaling pathway via death domain receptors

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

4 references

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

The death-associated protein kinases: structure, function, and beyond

protein phosphorylation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

8 April 2019

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

positive regulation of autophagy

1 reference

8 April 2019

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

cellular response to hydroperoxide

IMP

1 reference

8 April 2019

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53355

physically interacts with

IMP

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

346

protein kinase, ATP binding site

English

retrieved

17 August 2016

has part(s)

1 reference

Roc domain

1 reference

protein kinase domain

1 reference

ankyrin repeat

1 reference

serine/threonine-protein kinase, active site

1 reference

ankyrin repeat-containing domain

1 reference

Death domain

1 reference

Identifiers

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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13 November 2019

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9 August 2016

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9 August 2016