Protein tyrosine phosphatase non-receptor type 2 (Q21171735)

http://www.ebi.ac.uk/interpro/protein/P17706

Protein-tyrosine phosphatase-like

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17706

membrane protein

1 reference

inferred from GOA cell component → membrane

Tyrosine specific protein phosphatases domain, protein family

1 reference

PTP type protein phosphatase domain, protein family

1 reference

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

Protein-tyrosine phosphatase, active site, protein family

1 reference

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

1 reference

13 November 2019

1 reference

13 November 2019

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Evidence for a role of transmembrane protein p25 in localization of protein tyrosine phosphatase TC48 to the ER

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

phosphoprotein phosphatase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

Tyrosine phosphorylation of a SNARE protein, syntaxin 17: implications for membrane trafficking in the early secretory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

non-membrane spanning protein tyrosine phosphatase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

receptor tyrosine kinase binding

1 reference

8 April 2019

Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

protein tyrosine phosphatase activity

8 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

1 January 2018

Identification of a nuclear Stat1 protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

STAT family protein binding

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

protein tyrosine phosphatase activity

7 references

8 April 2019

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Identification of a nuclear Stat1 protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

4 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of epidermal growth factor receptor signaling pathway

IDA

biological process

1 reference

8 April 2019

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

positive regulation of PERK-mediated unfolded protein response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of interleukin-4-mediated signaling pathway

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of interleukin-6-mediated signaling pathway

negative regulation of cell population proliferation

1 reference

8 April 2019

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

regulation of interferon-gamma-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of protein tyrosine kinase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

regulation of hepatocyte growth factor receptor signaling pathway

1 reference

8 April 2019

Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

peptidyl-tyrosine dephosphorylation

5 references

31 January 2018

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Identification of a nuclear Stat1 protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

negative regulation of transcription by RNA polymerase II

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of tyrosine phosphorylation of STAT protein

5 references

31 January 2018

T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Identification of a nuclear Stat1 protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

Identification of a nuclear Stat1 protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

31 January 2018

The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17706&geneProductId=UniProtKB:P17706

cellular response to cytokine stimulus

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

peptidyl-tyrosine dephosphorylation

TAS

3 references

8 April 2019

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of interleukin-6-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706

negative regulation of interleukin-4-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17706