The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery (Q21183984)

16 August 2022

7

Nancy Holroyd

Nancy

Holroyd

1 reference

16 August 2022

Aude Gilabert

13

Aude

Gilabert

1 reference

16 August 2022

Gary I Saunders

22

Gary I

Saunders

1 reference

16 August 2022

Martin Hunt

14

Martin

Hunt

1 reference

16 August 2022

Isheng J Tsai

4

Isheng J

Tsai

1 reference

16 August 2022

Adam J Reid

20

Adam J

Reid

1 reference

16 August 2022

Collette Britton

10

Collette

Britton

1 reference

16 August 2022

James A Cotton

27

James A

Cotton

1 reference

16 August 2022

Eileen Devaney

12

Eileen

Devaney

1 reference

16 August 2022

James D Wasmuth

23

James D

Wasmuth

1 reference

16 August 2022

Roz Laing

1

Roz

Laing

1 reference

16 August 2022

Taisei Kikuchi

2

Taisei

Kikuchi

1 reference

16 August 2022

9

Helen

Beasley

Helen Beasley

1 reference

16 August 2022

5

Robin N

Beech

Robin N Beech

1 reference

16 August 2022

Adrian J Wolstenholme

24

Adrian

Wolstenholme

Adrian Wolstenholme

1 reference

16 August 2022

Axel Martinelli

3

Axel

Martinelli

1 reference

16 August 2022

Elizabeth Redman

6

Elizabeth

Redman

1 reference

16 August 2022

David J Bartley

8

David J

Bartley

1 reference

16 August 2022

David Curran

11

David

Curran

1 reference

16 August 2022

Frank Jackson

15

Frank

Jackson

1 reference

16 August 2022

Stephanie L Johnston

16

Stephanie L

Johnston

1 reference

16 August 2022

Ivan Kryukov

17

Ivan

Kryukov

1 reference

16 August 2022

Keyu Li

18

Keyu

Li

1 reference

16 August 2022

Alison A Morrison

19

Alison A

Morrison

1 reference

16 August 2022

Neil Sargison

21

Neil

Sargison

1 reference

16 August 2022

John S Gilleard

26

John S

Gilleard

1 reference

describes a project that uses

16 August 2022

language of work or name

English

0 references

publication date

2013

0 references

published in

Genome Biology

0 references

volume

14

0 references

page(s)

R88

0 references

issue

8

0 references

DESeq2

object named as

DESeq

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1186/gb-2013-14-8-r88

0 references

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

19 March 2017

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Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes

19 March 2017

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19 March 2017

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Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

19 March 2017

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Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases

19 March 2017

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A cholinergic-regulated circuit coordinates the maintenance and bi-stable states of a sensory-motor behavior during Caenorhabditis elegans male copulation

19 March 2017

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Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

19 March 2017

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Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing

19 March 2017

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The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake

19 March 2017

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Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans

19 March 2017

1 reference

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Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans

19 March 2017

1 reference

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Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel

19 March 2017

1 reference

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Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway

19 March 2017

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SignalP 4.0: discriminating signal peptides from transmembrane regions

19 March 2017

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CEGMA: a pipeline to accurately annotate core genes in eukaryotic genomes

7 April 2017

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InterProScan--an integration platform for the signature-recognition methods in InterPro

7 April 2017

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KAAS: an automatic genome annotation and pathway reconstruction server

7 April 2017

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A molecular evolutionary framework for the phylum Nematoda

7 April 2017

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An inconvenient truth: global worming and anthelmintic resistance.

7 April 2017

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WormBase 2012: more genomes, more data, new website

12 September 2017

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Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance.

12 September 2017

1 reference

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A global analysis of C. elegans trans-splicing

12 September 2017

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DETECT--a density estimation tool for enzyme classification and its application to Plasmodium falciparum.

12 September 2017

1 reference

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A metabolic signature of long life in Caenorhabditis elegans

12 September 2017

1 reference

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EFICAz2: enzyme function inference by a combined approach enhanced by machine learning

12 September 2017

1 reference

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Cytochrome P450 metabolism and inhibition: analysis for drug discovery

12 September 2017

1 reference

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Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor

12 September 2017

1 reference

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Intestinal transcriptomes of nematodes: comparison of the parasites Ascaris suum and Haemonchus contortus with the free-living Caenorhabditis elegans

12 September 2017

1 reference

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A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus

12 September 2017

1 reference

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A new class of anthelmintics effective against drug-resistant nematodes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Population genetics of anthelmintic resistance in parasitic nematodes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Vaccines against blood-feeding nematodes of humans and livestock

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Xenobiotic detoxification in the nematode Caenorhabditis elegans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Understanding anthelmintic resistance: the need for genomics and genetics.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

AUGUSTUS: ab initio prediction of alternative transcripts

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

ATP-binding cassette transporters are required for efficient RNA interference in Caenorhabditis elegans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Characterisation of Teladorsagia circumcincta microsatellites and their development as population genetic markers.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

The use of Caenorhabditis elegans in parasitic nematode research

12 September 2017

1 reference

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mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Drug resistance in nematodes of veterinary importance: a status report.

12 September 2017

1 reference

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A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans

12 September 2017

1 reference

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Caenorhabditis elegans: how good a model for veterinary parasites?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Caenorhabditis elegans and the study of gene function in parasites

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Genetic variability following selection of Haemonchus contortus with anthelmintics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

A tissue specific approach for analysis of membrane and secreted protein antigens from Haemonchus contortus gut and its application to diverse nematode species

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Host movement and the genetic structure of populations of parasitic nematodes.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Progress on vaccination against Haemonchus contortus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

PHYLOGENY FOR SPECIES OF HAEMONCHUS (NEMATODA: TRICHOSTRONGYLOIDEA): CONSIDERATIONS OF THEIR EVOLUTIONARY HISTORY AND GLOBAL BIOGEOGRAPHY AMONG CAMELIDAE AND PECORA (ARTIODACTYLA)

30 May 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Global patterns reveal strong population structure in Haemonchus contortus, a nematode parasite of domesticated ruminants

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Genetic diversity patterns of Haemonchus placei and Haemonchus contortus populations isolated from domestic ruminants in Brazil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Flow cytometry for parasite nematode genome size measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Microsatellites of the parasitic nematode Haemonchus contortus: polymorphism and linkage with a direct repeat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Abundant variation in microsatellites of the parasitic nematode Trichostrongylus tenuis and linkage to a tandem repeat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Synergism of rotenone by piperonyl butoxide in Haemonchus contortus and Trichostrongylus colubriformis in vitro: potential for drug-synergism through inhibition of nematode oxidative detoxification pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Aspartic proteases from the nematode Caenorhabditis elegans. Structural organization and developmental and cell-specific expression of asp-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FGB-2013-14-8-R88

Genetic diversity of levamisole receptor subunits in parasitic nematode species and abbreviated transcripts associated with resistance.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054779

Cloning, expression, purification and kinetics of trehalose-6-phosphate phosphatase of filarial parasite Brugia malayi

29 November 2018

1 reference

12 December 2020

Microsatellite analysis reveals marked genetic differentiation between Haemonchus contortus laboratory isolates and provides a rapid system of genetic fingerprinting

1 reference

12 December 2020

The epidemiology of abomasal nematodes of sheep in Sweden, with particular reference to over-winter survival strategies

1 reference

12 December 2020

Purification and evaluation of the integral membrane protein H11 as a protective antigen against Haemonchus contortus

1 reference

12 December 2020

Vitamin B12 changes in Nippostrongylus brasiliensis in its free-living and parasitic habitats with biochemical implications

1 reference

12 December 2020

Immunisation of sheep with an integral membrane glycoprotein complex of Haemonchus contortus and with its major polypeptide components

1 reference

12 December 2020

Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda)

1 reference

12 December 2020

Measurements of blood loss caused by Haemonchus contortus infection in sheep

1 reference

12 December 2020

Vaccination against Haemonchus contortus: performance of native parasite gut membrane glycoproteins in Merino lambs grazing contaminated pasture

1 reference

12 December 2020

Identifiers

DOI

10.1186/GB-2013-14-8-R88

1 reference

1715381

0 references

1715381

1 reference

1 reference

1 reference