WASH complex subunit 1 (Q21245851)

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mammalian protein found in Homo sapiens

family with sequence similarity 39, member E
FLJ00075 protein
actin nucleation promoting factor
WASHC1
Protein FAM39E
WAS protein family homolog 1
CXYorf1-like protein on chromosome 9

Language	Label	Description	Also known as
English	WASH complex subunit 1	mammalian protein found in Homo sapiens	family with sequence similarity 39, member E FLJ00075 protein actin nucleation promoting factor WASHC1 Protein FAM39E WAS protein family homolog 1 CXYorf1-like protein on chromosome 9

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A8K0Z3

transporter of unknown biochemical mechanism

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

WASH1, WAHD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

5 references

8 April 2019

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

A FAM21-containing WASH complex regulates retromer-dependent sorting

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

ubiquitin protein ligase binding

determination method

1 reference

8 April 2019

Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

early endosome membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

recycling endosome membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

intracellular membrane-bounded organelle

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

recycling endosome

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

biological process

positive regulation of cell migration

determination method

1 reference

8 April 2019

The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

extracellular matrix disassembly

determination method

1 reference

8 April 2019

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

positive regulation of pseudopodium assembly

determination method

1 reference

8 April 2019

The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

Arp2/3 complex-mediated actin nucleation

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

8 April 2019

Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

protein transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

determination method

1 reference

8 April 2019

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

negative regulation of autophagy

determination method

1 reference

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

endosomal transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

regulation of protein ubiquitination

determination method

1 reference

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

negative regulation of phosphatidylinositol 3-kinase activity

determination method

1 reference

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A8K0Z3

determination method

WASH1, WAHD domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/A8K0Z3

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

8 February 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000485627

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485627

ENSP00000494459

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494459

Transporter Classification Database ID

1 reference

Transporter Classification database

29 April 2020

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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