Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk (Q21263140)

18 August 2022

6

H E Varmus

Harold E

Varmus

1 reference

18 August 2022

M Chamorro

1

Mario

Chamorro

1 reference

18 August 2022

M J Czar

2

Michael J

Czar

1 reference

18 August 2022

G Cheng

4

Genhong

Cheng

1 reference

18 August 2022

M J Lenardo

5

Michael J

Lenardo

1 reference

18 August 2022

P L Schwartzberg

7

Pamela L

Schwartzberg

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2172-2-3

18 August 2022

language of work or name

English

0 references

publication date

2001

0 references

published in

BMC Immunology

0 references

volume

2

0 references

issue

1

0 references

page(s)

3

0 references

exact match

0 references

cites work

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TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12

19 March 2017

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19 March 2017

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Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

19 March 2017

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Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

19 March 2017

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Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

19 March 2017

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Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

19 March 2017

1 reference

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Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

19 March 2017

1 reference

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Regulation of Btk function by a major autophosphorylation site within the SH3 domain

19 March 2017

1 reference

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Tec protein-tyrosine kinase is an effector molecule of Lyn protein-tyrosine kinase

19 March 2017

1 reference

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Proline-rich sequences that bind to Src homology 3 domains with individual specificities

19 March 2017

1 reference

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A novel protein-tyrosine kinase, tec, is preferentially expressed in liver

19 March 2017

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Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement

19 March 2017

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Production of high-titer helper-free retroviruses by transient transfection

19 March 2017

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Signal transduction by lymphocyte antigen receptors

7 April 2017

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T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase

7 April 2017

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Tec family kinases in lymphocyte signaling and function

12 September 2017

1 reference

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Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

12 September 2017

1 reference

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Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

12 September 2017

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In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies

12 September 2017

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rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases

12 September 2017

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Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

12 September 2017

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The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

12 September 2017

1 reference

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Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases

12 September 2017

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Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors

12 September 2017

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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

12 September 2017

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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

12 September 2017

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The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

12 September 2017

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An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo

12 September 2017

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Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase

12 September 2017

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Murine txk: a protein tyrosine kinase gene regulated by T cell activation.

12 September 2017

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IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases

12 September 2017

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CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Complex complexes: signaling at the TCR.

27 September 2017

1 reference

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The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Membrane compartmentation is required for efficient T cell activation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

Btk function in B cell development and response.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31577

The Itk/Btk/Tec family of protein-tyrosine kinases

29 November 2018

1 reference

12 December 2020

Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon Activation of mature T lymphocytes

1 reference

12 December 2020

In vitro recombination and mutagenesis of DNA. SOEing together tailor-made genes

1 reference

12 December 2020

Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation

1 reference

12 December 2020

The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease

1 reference

12 December 2020

Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2172-2-3

1 reference

3932242

0 references

3932242

1 reference

1 reference

1 reference