PCI-24781, a Novel Hydroxamic Acid HDAC Inhibitor, Exerts Cytotoxicity and Histone Alterations via Caspase-8 and FADD in Leukemia Cells (Q21328686)

1

Nilsa

Rivera-Del Valle

1 reference

16 September 2022

Shan Gao

2

Shan

Gao

1 reference

16 September 2022

Claudia P Miller

3

Claudia P

Miller

1 reference

16 September 2022

Joy Fulbright

4

Joy

Fulbright

1 reference

16 September 2022

Carolina Gonzales

5

Carolina

Gonzales

1 reference

16 September 2022

Mint Sirisawad

6

Mint

Sirisawad

1 reference

16 September 2022

Susanne Steggerda

7

Susanne

Steggerda

1 reference

16 September 2022

Jennifer Wheler

8

Jennifer

Wheler

1 reference

16 September 2022

Sriram Balasubramanian

9

Sriram

Balasubramanian

1 reference

16 September 2022

Joya Chandra

10

Joya

International Journal of Cell Biology

Chandra

1 reference

16 September 2022

language of work or name

English

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publication date

2010

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published in

1 reference

Creative Commons Attribution 3.0 Unported

PubMed

volume

2010

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page(s)

207420

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copyright license

start time

1 January 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

cites work

PCI-24781 induces caspase and reactive oxygen species-dependent apoptosis through NF-kappaB mechanisms and is synergistic with bortezomib in lymphoma cells

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

7 April 2017

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Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells

12 September 2017

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Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies

12 September 2017

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Histone tail modifications and noncanonical functions of histones: perspectives in cancer epigenetics

12 September 2017

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Valproic acid sensitizes chronic lymphocytic leukemia cells to apoptosis and restores the balance between pro- and antiapoptotic proteins

12 September 2017

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HDAC6 at the intersection of autophagy, the ubiquitin-proteasome system and neurodegeneration

12 September 2017

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Histone deacetylase inhibitors: molecular mechanisms of action

12 September 2017

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Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma

12 September 2017

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NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells

12 September 2017

1 reference

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CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo

12 September 2017

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Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance

12 September 2017

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Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling

12 September 2017

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Caspase-8 cleaves histone deacetylase 7 and abolishes its transcription repressor function

27 September 2017

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Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway?

27 September 2017

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Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP.

27 September 2017

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FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells

27 September 2017

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Apoptotic release of histones from nucleosomes

27 September 2017

1 reference

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Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2010%2F207420

The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2010%2F207420

21 January 2018

Identifiers

DOI

10.1155/2010/207420

1 reference

release_3cee34y76jbjhibn7rctvq5y24

2250598

Fatcat ID

0 references

2250598

1 reference

1 reference

1 reference