DnaJ heat shock protein family (Hsp40) member B6 (Q21493886)

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mammalian protein found in Mus musculus

mDj4
MRJ
heat shock protein J2
HSJ-2
mammalian relative of DnaJ
Dnajb6
dnaJ homolog subfamily B member 6
DnaJ (Hsp40) homolog, subfamily B, member 6

Language	Label	Description	Also known as
English	DnaJ heat shock protein family (Hsp40) member B6	mammalian protein found in Mus musculus	mDj4 MRJ heat shock protein J2 HSJ-2 mammalian relative of DnaJ Dnajb6 dnaJ homolog subfamily B member 6 DnaJ (Hsp40) homolog, subfamily B, member 6

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Chaperone J-domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O54946

DnaJ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DnaJ domain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

protein folding chaperone activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

protein binding

determination method

3 references

14 February 2019

Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Bioinformatics and cellular signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

identical protein binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

chaperone binding

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

determination method

3 references

perinuclear region of cytoplasm

determination method

3 references

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

biological process

chorion development

determination method

1 reference

14 February 2019

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

extracellular matrix organization

determination method

1 reference

14 February 2019

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

chorio-allantoic fusion

determination method

1 reference

14 February 2019

Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

protein localization to nucleus

determination method

1 reference

14 February 2019

The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

negative regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

determination method

1 reference

14 February 2019

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

actin cytoskeleton organization

determination method

1 reference

14 February 2019

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

chaperone-mediated protein folding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

positive regulation of ATP-dependent activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

protein folding

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54946

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O54946

DnaJ domain, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O54946

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000008733

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000008733

ENSMUSP00000110488

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000110488

ENSMUSP00000012734

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000012734

ENSMUSP00000117159

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000117159

ENSMUSP00000142783

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142783

ENSMUSP00000142878

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142878

ENSMUSP00000143639

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143639

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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