Interferon beta 1, fibroblast (Q21494546)

http://www.ebi.ac.uk/interpro/protein/P01575

four-helical cytokine-like, core

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01575

1 reference

25 May 2022

1 reference

25 May 2022

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

24 April 2018

Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

cytokine receptor binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

type I interferon receptor binding

IEA

1 reference

24 April 2018

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

chloramphenicol O-acetyltransferase activity

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

type I interferon receptor binding

3 references

9 May 2019

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

cellular response to virus

biological process

1 reference

9 May 2019

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

IEA

adaptive immune response

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

cytokine-mediated signaling pathway

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

cellular response to dsRNA

1 reference

9 May 2019

Toll-like receptor 3 activation induces antiviral immune responses in mouse sertoli cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

cellular response to dexamethasone stimulus

IEP

1 reference

9 May 2019

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

natural killer cell activation involved in immune response

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

1 reference

24 April 2018

Critical roles for IFN-β in lymphoid development, myelopoiesis, and tumor development: Links to tumor necrosis factor α

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

IMP

humoral immune response

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

defense response to bacterium

1 reference

9 May 2019

Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

B cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

T cell activation involved in immune response

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

innate immune response

1 reference

24 April 2018

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

B cell activation involved in immune response

IEA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

cellular response to interferon-beta

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

negative regulation of viral genome replication

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

negative regulation of T cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

type I interferon signaling pathway

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01575&geneProductId=UniProtKB:P01575

negative regulation of T-helper 2 cell cytokine production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

positive regulation of apoptotic signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

negative regulation of osteoclast differentiation

1 reference

9 May 2019

Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

macrophage activation involved in immune response

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

defense response to virus

3 references

9 May 2019

The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575

9 May 2019

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01575