Guanine nucleotide binding protein, alpha q polypeptide (Q21494796)

http://www.ebi.ac.uk/interpro/protein/P21279

G-protein alpha subunit, group Q

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P21279

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P21279

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

1 reference

25 May 2022

GTPase activator activity

3 references

24 April 2018

Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

24 April 2018

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

guanyl nucleotide binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

G protein-coupled receptor binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

8 references

14 February 2019

Structural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq Complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

alkylglycerophosphoethanolamine phosphodiesterase activity

IPI

1 reference

14 February 2019

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

2 references

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

4 references

14 February 2019

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

heterotrimeric G-protein complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

protein-containing complex

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

heterotrimeric G-protein complex

3 references

14 February 2019

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

developmental pigmentation

biological process

1 reference

14 February 2019

Effects of G-protein mutations on skin color

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

forebrain neuron development

1 reference

14 February 2019

Heterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

phospholipase C-activating dopamine receptor signaling pathway

1 reference

14 February 2019

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

adenylate cyclase-activating G protein-coupled receptor signaling pathway

IGI

1 reference

24 April 2018

Transgenic replacement of type V adenylyl cyclase identifies a critical mechanism of beta-adrenergic receptor dysfunction in the G alpha q overexpressing mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

embryonic digit morphogenesis

IDA

1 reference

14 February 2019

Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

regulation of melanocyte differentiation

IGI

1 reference

14 February 2019

Effects of G-protein mutations on skin color

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

1 reference

14 February 2019

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

skeletal system development

1 reference

14 February 2019

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

glutamate receptor signaling pathway

1 reference

24 April 2018

G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

1 reference

24 April 2018

Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21279&geneProductId=UniProtKB:P21279

1 reference

14 February 2019

Heterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

post-embryonic development

1 reference

14 February 2019

Heterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

2 references

protein heterotrimerization

1 reference

14 February 2019

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

positive regulation of GTPase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

activation of phospholipase C activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

negative regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

negative regulation of potassium ion transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

positive regulation of smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

negative regulation of protein kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

adenylate cyclase-activating G protein-coupled receptor signaling pathway

glutamate receptor signaling pathway

IDA

protein stabilization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21279

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016