CREB-binding protein (Q21494907)

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mouse protein (annotated by UniProtKB/Swiss-Prot P45481)
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English
CREB-binding protein
mouse protein (annotated by UniProtKB/Swiss-Prot P45481)

    Statements

    instance of
    protein
    0 references
    part of
    molecular function
    protein binding
    determination method
    IPI
    41 references
    retrieved
    14 February 2019
    stated in
    A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) binds to, and inhibits transactivation of, CREB-binding protein
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    SUMO interaction motifs in Sizn1 are required for promyelocytic leukemia protein nuclear body localization and for transcriptional activation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Identification of novel CBP interacting proteins in embryonic orofacial tissue
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    SEI family of nuclear factors regulates p53-dependent transcriptional activation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Novel interaction between nuclear co-activator CBP and the CDK5 activator binding protein - C53
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Inactivating mutations of acetyltransferase genes in B-cell lymphoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    The corepressor activity of Alien is controlled by CREB-binding protein/p300
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Modulation of allostery by protein intrinsic disorder
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Acetylation is indispensable for p53 activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    The CH2 domain of CBP/p300 is a novel zinc finger
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) binds to, and inhibits transactivation of, CREB-binding protein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    retrieved
    14 February 2019
    stated in
    Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IPI
    histone acetyltransferase activity
    determination method
    IEA
    ISS
    ISO
    IDA
    TAS
    7 references
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    TAS
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    ISS
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    ISO
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IEA
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IEA
    retrieved
    14 February 2019
    stated in
    Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA
    retrieved
    14 February 2019
    stated in
    Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA
    cell component
    biological process
    positive regulation of transcription, DNA-templated
    determination method
    IDA
    ISS
    ISO
    6 references
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    ISS
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    ISO
    retrieved
    14 February 2019
    stated in
    Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) binds to, and inhibits transactivation of, CREB-binding protein
    GOA
    curator
    UniProt
    UniProt protein ID
    P45481
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA
    retrieved
    14 February 2019
    stated in
    HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA
    retrieved
    14 February 2019
    stated in
    Functional interaction between Smad, CREB binding protein, and p68 RNA helicase
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA
    retrieved
    14 February 2019
    stated in
    The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45481
    determination method
    IDA

    Identifiers

    PDB structure ID
     
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