E74-like factor 3 (Q21495278)

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mammalian protein found in Mus musculus

Elf3
epithelial-restricted with serine box
epithelium-restricted Ets protein ESX
epithelium-specific Ets transcription factor 1
ESE-1
ETS-related transcription factor Elf-3

Language	Label	Description	Also known as
English	E74-like factor 3	mammalian protein found in Mus musculus	Elf3 epithelial-restricted with serine box epithelium-restricted Ets protein ESX epithelium-specific Ets transcription factor 1 ESE-1 ETS-related transcription factor Elf-3

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

ETS-related transcription factor Elf-3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

Sterile alpha motif/pointed domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

Pointed domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

sequence-specific DNA binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

DNA-binding transcription factor activity

determination method

3 references

14 February 2019

Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

transcription coactivator activity

determination method

3 references

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method

4 references

10 September 2018

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UPW2&geneProductId=UniProtKB:Q3UPW2

determination method

10 September 2018

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UPW2&geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

2 references

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

Golgi apparatus

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

biological process

regulation of transcription, DNA-templated

determination method

3 references

14 February 2019

Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

epithelial cell differentiation

determination method

3 references

anatomical structure morphogenesis

determination method

1 reference

14 February 2019

Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

extracellular matrix organization

determination method

1 reference

14 February 2019

Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

transcription by RNA polymerase II

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UPW2&geneProductId=UniProtKB:Q3UPW2

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

positive regulation of transcription, DNA-templated

determination method

3 references

inflammatory response

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

blastocyst development

determination method

1 reference

14 February 2019

The role of ETS transcription factors in transcription and development of mouse preimplantation embryos

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

The role of ETS transcription factors in transcription and development of mouse preimplantation embryos

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

14 February 2019

Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

mammary gland involution

determination method

1 reference

14 February 2019

The epithelium-specific ets transcription factor ESX is associated with mammary gland development and involution

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UPW2

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q3UPW2

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000003135

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000003135

ENSMUSP00000139769

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000139769

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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