Deiodinase, iodothyronine type III (Q21496533)

http://www.ebi.ac.uk/interpro/protein/Q91ZI8

Iodothyronine deiodinase I/III

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q91ZI8

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Iodothyronine deiodinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

oxidoreductase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

thyroxine 5'-deiodinase activity

3 references

16 July 2018

The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZI8&geneProductId=UniProtKB:Q91ZI8

16 July 2018

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZI8&geneProductId=UniProtKB:Q91ZI8

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZI8&geneProductId=UniProtKB:Q91ZI8

thyroxine 5-deiodinase activity

3 references

14 February 2019

Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

thyroxine 5'-deiodinase activity

IDA

4 references

14 February 2019

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

integral component of membrane

IBA

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

thyroid hormone catabolic process

biological process

3 references

14 February 2019

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

14 February 2019

Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

hormone biosynthetic process

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

positive regulation of multicellular organism growth

1 reference

14 February 2019

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

1 reference

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

retinal cone cell development

1 reference

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

negative regulation of eye photoreceptor cell development

1 reference

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

retinal cone cell apoptotic process

1 reference

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

thyroid hormone metabolic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

macromolecule metabolic process

IBA

1 reference

14 February 2019

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZI8

Iodothyronine deiodinase, active site

IDA

has part(s)

1 reference

stated in

InterPro Release 71.0