Diaphanous related formin 1 (Q21497084)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Mus musculus

• DRF1
• Diaphanous-related formin-1
• Dia1
• Diaph1
• p140mDIA
• MDia1
• protein diaphanous homolog 1

edit

Language	Label	Description	Also known as
English	Diaphanous related formin 1	mammalian protein found in Mus musculus	DRF1 Diaphanous-related formin-1 Dia1 Diaph1 p140mDIA MDia1 protein diaphanous homolog 1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O08808

part of

Formin, protein diaphanous homologue 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Armadillo-like helical

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Armadillo-type fold

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Formin, FH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DRF autoregulatory, protein family

1 reference

based on heuristic

inferred from protein domain or family

Formin, GTPase-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Diaphanous autoregulatory (DAD) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Formin, FH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

1z2c asr r 500.jpeg
500 × 500; 46 KB

1 reference

imported from Wikimedia project

English Wikipedia

Wikimedia import URL

https://en.wikipedia.org/w/index.php?title=MDia1&oldid=874560810

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O08808

encoded by

Diaph1

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O08808

molecular function

profilin binding

determination method

IDA

1 reference

retrieved

14 February 2019

stated in

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

transmembrane transporter binding

determination method

ISO

IPI

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

retrieved

14 February 2019

stated in

PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

protein binding

determination method

IPI

7 references

retrieved

14 February 2019

stated in

Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

actin binding

determination method

IDA

IEA

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

identical protein binding

determination method

IPI

3 references

retrieved

14 February 2019

stated in

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

Structure of the autoinhibitory switch in formin mDia1.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

retrieved

14 February 2019

stated in

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IPI

cell component

cytoplasm

determination method

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08808&geneProductId=UniProtKB:O08808

determination method

IEA

cell projection

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

membrane

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

plasma membrane

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

spindle

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

microtubule organizing center

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

ruffle membrane

determination method

IDA

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

brush border

determination method

IDA

1 reference

retrieved

14 February 2019

stated in

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

neuron projection

determination method

IDA

1 reference

retrieved

14 February 2019

stated in

Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

mitotic spindle

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

cytoskeleton

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

nucleus

determination method

IDA

1 reference

retrieved

10 September 2018

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08808&geneProductId=UniProtKB:O08808

determination method

IDA

cytoplasm

determination method

IDA

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

nucleus

determination method

IDA

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

biological process

actin filament organization

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

regulation of release of sequestered calcium ion into cytosol

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

hearing

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

actin filament polymerization

determination method

IDA

IEA

3 references

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

retrieved

14 February 2019

stated in

The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

brain development

determination method

IMP

1 reference

retrieved

14 February 2019

stated in

Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IMP

regulation of microtubule-based process

determination method

ISS

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

protein localization to microtubule

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

cytoskeleton organization

determination method

ISS

ISO

2 references

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08808&geneProductId=UniProtKB:O08808

determination method

ISS

retrieved

24 April 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08808&geneProductId=UniProtKB:O08808

determination method

ISO

regulation of cell shape

determination method

ISS

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

cellular component organization

determination method

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

neuron projection development

determination method

IDA

1 reference

retrieved

14 February 2019

stated in

Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

actin cytoskeleton organization

determination method

IDA

IEA

3 references

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IEA

retrieved

14 February 2019

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

retrieved

14 February 2019

stated in

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

cellular response to histamine

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

regulation of cytoskeleton organization

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

positive regulation of cell migration

determination method

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

cytoskeleton organization

determination method

IDA

ISO

ISS

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

ISO

retrieved

14 February 2019

stated in

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

GOA

curator

UniProt

UniProt protein ID

O08808

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08808

determination method

IDA

has part(s)

Formin, FH2 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Formin, FH3 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Rho GTPase-binding/formin homology 3 (GBD/FH3) domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Diaphanous autoregulatory (DAD) domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Formin, GTPase-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

DRF autoregulatory

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O08808

Identifiers

RefSeq protein ID

NP_001292909

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13367

NP_001292910

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13367

NP_031884

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13367

XP_036016863

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

13367

UniProt protein ID

O08808

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O08808

Ensembl protein ID

ENSMUSP00000111297

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000111297

ENSMUSP00000025337

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000025337

ENSMUSP00000078942

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000078942

ENSMUSP00000111292

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000111292

ENSMUSP00000111294

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000111294

Freebase ID

/m/0cmcq4w

0 references

Microsoft Academic ID

59999672

0 references

OpenAlex ID

C59999672

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1V9D

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

1Z2C

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

2BAP

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

2BNX

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

2F31

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

2V8F

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

3EG5

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

3O4X

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

3OBV

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

4UWX

1 reference

stated in

UniProt

UniProt protein ID

O08808

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21497084&oldid=2174117215"