Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Q21498539)

http://www.ebi.ac.uk/interpro/protein/Q6R0H7

G-protein alpha subunit, group S

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6R0H7

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6R0H7

1 reference

9 August 2016

1 reference

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

3 references

14 February 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

alkylglycerophosphoethanolamine phosphodiesterase activity

IPI

1 reference

14 February 2019

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

guanyl nucleotide binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

signal transducer activity

IEA

3 references

24 April 2018

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

24 April 2018

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

G-protein alpha-subunit binding

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

3 references

protein domain specific binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

G-protein beta-subunit binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

alpha-tubulin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

G protein-coupled receptor binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

4 references

14 February 2019

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

adenylate cyclase activator activity

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Targeted disruption of Gnas in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

apical plasma membrane

1 reference

14 February 2019

intrinsic component of membrane

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

trans-Golgi network membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

perinuclear region of cytoplasm

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

heterotrimeric G-protein complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

2 references

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

heterotrimeric G-protein complex

3 references

14 February 2019

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

COPI-coated Golgi to ER transport vesicle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

skeletal system development

biological process

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

adenylate cyclase-activating G protein-coupled receptor signaling pathway

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Targeted disruption of Gnas in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Identification of the lesion in the stimulatory GTP-binding protein of the uncoupled S49 lymphoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Golf: an olfactory neuron specific-G protein involved in odorant signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

multicellular organism growth

IDA

1 reference

14 February 2019

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of osteoclast differentiation

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

endochondral ossification

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

post-embryonic development

post-embryonic body morphogenesis

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

regulation of parathyroid hormone secretion

1 reference

14 February 2019

Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

cartilage development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of osteoblast differentiation

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

sensory perception of chemical stimulus

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6R0H7&geneProductId=UniProtKB:Q6R0H7

embryonic cranial skeleton morphogenesis

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

energy reserve metabolic process

1 reference

14 February 2019

Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

2 references

1 reference

14 February 2019

Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

embryonic hindlimb morphogenesis

1 reference

14 February 2019

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

regulation of signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of GTPase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of cAMP-mediated signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

response to parathyroid hormone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

adenylate cyclase-activating adrenergic receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

G protein-coupled receptor signaling pathway

positive regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of sodium ion transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

negative regulation of renal sodium excretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

negative regulation of blood pressure

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

calcium ion homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

cellular response to prostaglandin E stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

cellular response to catecholamine stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

adenylate cyclase-activating dopamine receptor signaling pathway

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

hair follicle placode formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6R0H7

Identifiers

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016