CCAAT/enhancer binding protein (C/EBP), gamma (Q21499244)

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mammalian protein found in Mus musculus

GPE1-BP
IG/EBP-1
Cebpg
G-CSF promoter element 1 binding protein
granulocyte colony-stimulating factor promoter element 1-binding protein
CCAAT/enhancer-binding protein gamma
GPE1-binding protein
immunoglobulin enhancer-binding protein 1
GPE1-BP (C/EBP gamma)
c/EBP gamma

Language	Label	Description	Also known as
English	CCAAT/enhancer binding protein (C/EBP), gamma	mammalian protein found in Mus musculus	GPE1-BP IG/EBP-1 Cebpg G-CSF promoter element 1 binding protein granulocyte colony-stimulating factor promoter element 1-binding protein CCAAT/enhancer-binding protein gamma GPE1-binding protein immunoglobulin enhancer-binding protein 1 GPE1-BP (C/EBP gamma) c/EBP gamma

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

sequence-specific DNA binding

determination method

3 references

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

transcription factor binding

determination method

3 references

14 February 2019

Cloning of the cDNA encoding human C/EBPγ, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

C/EBPdelta and C/EBPgamma bind the CCAAT-box in the human beta-globin promoter and modulate the activity of the CACC-box binding protein, EKLF

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

protein heterodimerization activity

determination method

3 references

protein homodimerization activity

determination method

1 reference

14 February 2019

Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

biological process

chromatin remodeling

determination method

1 reference

14 February 2019

Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

negative regulation of DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

transcription, DNA-templated

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53568&geneProductId=UniProtKB:P53568

determination method

nucleosome disassembly

determination method

1 reference

14 February 2019

Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

enucleate erythrocyte differentiation

determination method

1 reference

14 February 2019

Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

immune response

determination method

1 reference

14 February 2019

Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

mRNA metabolic process

determination method

1 reference

14 February 2019

Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha)

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

liver development

determination method

2 references

B cell differentiation

determination method

1 reference

14 February 2019

The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

natural killer cell mediated cytotoxicity

determination method

1 reference

14 February 2019

Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53568

determination method

transcription by RNA polymerase II

determination method

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53568&geneProductId=UniProtKB:P53568

determination method

Basic-leucine zipper domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P53568

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000064963

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000064963

ENSMUSP00000118588

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118588

Sitelinks

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