Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Q21499275)

http://www.ebi.ac.uk/interpro/protein/O35740

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

1 reference

14 February 2019

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

transcription coregulator activity

1 reference

14 February 2019

Folic acid prevents exencephaly in Cited2 deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

transcription corepressor activity

TAS

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

3 references

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

3 references

14 February 2019

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

histone acetyltransferase binding

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

transcription coactivator activity

IPI

7 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

protein domain specific binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

transcription coactivator activity

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

7 references

21 June 2018

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

21 June 2018

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

16 July 2018

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of transforming growth factor beta receptor signaling pathway

IBA

biological process

1 reference

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

cranial nerve morphogenesis

1 reference

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

regulation of transcription by RNA polymerase II

1 reference

16 July 2018

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

cardiac neural crest cell development involved in heart development

1 reference

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

embryonic process involved in female pregnancy

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique

blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

granulocyte differentiation

1 reference

14 February 2019

Cited2 is required for normal hematopoiesis in the murine fetal liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

cell population proliferation

ISS

transforming growth factor beta receptor signaling pathway

2 references

1 reference

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

pulmonary artery morphogenesis

1 reference

14 February 2019

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

cardiac septum morphogenesis

1 reference

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

ventricular septum morphogenesis

1 reference

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

in utero embryonic development

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

morphogenesis of an epithelium

1 reference

14 February 2019

Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of transcription, DNA-templated

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 modulates TGF-beta-mediated upregulation of MMP9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

3 references

14 February 2019

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

14 February 2019

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

central nervous system development

1 reference

14 February 2019

Folic acid prevents exencephaly in Cited2 deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of cell cycle

1 reference

14 February 2019

MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

regulation of animal organ formation

1 reference

14 February 2019

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

lens morphogenesis in camera-type eye

1 reference

14 February 2019

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

The transcription co-factor CITED2 functions during sex determination and early gonad development

sex-determination system

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

embryonic camera-type eye morphogenesis

1 reference

14 February 2019

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

IGI

neural tube formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

1 reference

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

adrenal cortex formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

The transcription co-factor CITED2 functions during sex determination and early gonad development

male gonad development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

peripheral nervous system development

IGI

1 reference

14 February 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of cell-cell adhesion

1 reference

14 February 2019

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

endocardial cushion development

1 reference

14 February 2019

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

embryonic placenta development

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

negative regulation of apoptotic process

1 reference

14 February 2019

Cited2, a coactivator of HNF4alpha, is essential for liver development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

response to fluid shear stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

2 references

negative regulation of cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

trophectodermal cell differentiation

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

hematopoietic progenitor cell differentiation

1 reference

14 February 2019

Cited2 is required for normal hematopoiesis in the murine fetal liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

skeletal muscle cell differentiation

1 reference

14 February 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

negative regulation of transcription from RNA polymerase II promoter in response to hypoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of male gonad development

1 reference

14 February 2019

The transcription co-factor CITED2 functions during sex determination and early gonad development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

2 references

determination of heart left/right asymmetry

1 reference

14 February 2019

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

embryonic heart tube left/right pattern formation

1 reference

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

adrenal gland development

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

determination of left/right symmetry

1 reference

14 February 2019

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

1 reference

14 February 2019

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

leukocyte differentiation

1 reference

14 February 2019

Cited2 is required for normal hematopoiesis in the murine fetal liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

left/right axis specification

1 reference

14 February 2019

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

Cited2 is required for normal hematopoiesis in the murine fetal liver

erythrocyte development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

response to mechanical stimulus

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

cellular response to growth factor stimulus

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35740

positive regulation of gene expression

3 references

negative regulation of gene expression

3 references

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740

positive regulation of nucleic acid-templated transcription

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35740&geneProductId=UniProtKB:O35740