Chapter 7: Pharmacogenomics (Q21563496)

20 September 2022

Konrad J Karczewski

1

Konrad J

Karczewski

1 reference

20 September 2022

3

Russ B Altman

Russ B

Altman

1 reference

23300409

PLOS Computational Biology

20 September 2022

language of work or name

English

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publication date

2012

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published in

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volume

8

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issue

12

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page(s)

e1002817

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copyright license

Creative Commons Attribution 4.0 International

start time

27 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

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Recent progress in automatically extracting information from the pharmacogenomic literature

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An integrative method for scoring candidate genes from association studies: application to warfarin dosing

12 September 2017

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A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans

12 September 2017

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Docking and chemoinformatic screens for new ligands and targets

12 September 2017

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Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

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12 September 2017

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Pharmacogenetic tests in asthma therapy

12 September 2017

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Relationship between tamoxifen use and high risk endometrial cancer histologic types

12 September 2017

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Chronic heart failure: beta-blockers and pharmacogenetics

12 September 2017

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Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia

12 September 2017

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HLA-B*5701 screening for hypersensitivity to abacavir

12 September 2017

1 reference

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Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

12 September 2017

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VKORC1: molecular target of coumarins

12 September 2017

1 reference

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The pharmacogenetics research network: from SNP discovery to clinical drug response.

12 September 2017

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ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.

12 September 2017

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Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis

12 September 2017

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Pharmacogenetics and drug development: the path to safer and more effective drugs

12 September 2017

1 reference

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The ABC transporter structure and mechanism: perspectives on recent research.

12 September 2017

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ABC of oral bioavailability: transporters as gatekeepers in the gut.

12 September 2017

1 reference

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Overcoming Multidrug Resistance in Cancer: An Update on the Clinical Strategy of Inhibiting P-Glycoprotein

12 September 2017

1 reference

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Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

12 September 2017

1 reference

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Pharmacogenomics: translating functional genomics into rational therapeutics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Identification of two different point mutations associated with the fluoride-resistant phenotype for human butyrylcholinesterase

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Genomic-directed targeted therapy increases endometrial cancer cell sensitivity to doxorubicin

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Learning from product labels and label changes: how to build pharmacogenomics into drug-development programs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single-drug pharmacogenetics

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Biochemical basis of hereditary resistance to warfarin in the rat.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531317

With your genes? Take one of these, three times a day

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

21 January 2018

When good drugs go bad.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

Pharmacogenomics: "noninferiority" is sufficient for initial implementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002817

Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23300409

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23300409

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1002817

0 references

DBLP publication ID

journals/ploscb/KarczewskiDA12

1 reference

DBLP Dataset 2021-01-02

release_bd3mmll7cvad7jwdhsy6amou4u

28 January 2021

Fatcat ID

0 references

PMC publication ID

3531317

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