Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy (Q21710681)

Trends in Molecular Medicine

Europe PubMed Central

title

Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy (English)

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1 reference

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Hugo F. Mendes

1

Hugo F

Mendes

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7 February 2023

Jacqueline van der Spuy

series ordinal

2

author given names

Jacqueline

author last names

van der Spuy

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7 February 2023

J. Paul Chapple

series ordinal

3

author given names

J Paul

author last names

Chapple

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7 February 2023

Michael E. Cheetham

series ordinal

4

author given names

Michael E

author last names

Cheetham

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7 February 2023

language of work or name

English

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publication date

April 2005

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published in

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volume

11

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issue

4

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page(s)

177-185

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cites work

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AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse

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Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa

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Constitutive opsin signaling: night blindness or retinal degeneration?

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Dark adaptation and the retinoid cycle of vision

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The carboxyl-terminal domain is essential for rhodopsin transport in rod photoreceptors

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Opsin localization and rhodopsin photochemistry in a transgenic mouse model of retinitis pigmentosa

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Aggresomes, inclusion bodies and protein aggregation

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Phototransduction: crystal clear

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Unfolding retinal dystrophies: a role for molecular chaperones?

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Rhodopsin maturation antagonized by dominant rhodopsin mutants.

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Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa

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Rhodopsin arginine-135 mutants are phosphorylated by rhodopsin kinase and bind arrestin in the absence of 11-cis-retinal

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Accelerated transport and maturation of lysosomal α–galactosidase A in Fabry lymphoblasts by an enzyme inhibitor

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Polyglutamine protein aggregates are dynamic

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Activation of mislocalized opsin kills rod cells: a novel mechanism for rod cell death in retinal disease

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Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.

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Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa

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Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration

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bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations

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Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments

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Effect of vitamin A supplementation on rhodopsin mutants threonine-17 --> methionine and proline-347 --> serine in transgenic mice and in cell cultures

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A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

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The Chaperone Environment at the Cytoplasmic Face of the Endoplasmic Reticulum Can Modulate Rhodopsin Processing and Inclusion Formation

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Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H.

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Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

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Suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa

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Identification of an outer segment targeting signal in the COOH terminus of rhodopsin using transgenic Xenopus laevis

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A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment

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Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration

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Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage.

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7 January 2021

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Identifiers

DOI

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OpenCitations bibliographic resource ID

1874972

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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30 July 2022