Distal-less homeobox 2 (Q21981330)

Homeobox domain, protein family

1 reference

Distal-less-like homeobox protein, N-terminal domain, protein family

1 reference

basic helix-loop-helix transcription factor

1 reference

Helix-turn-helix motif, protein family

1 reference

Homeobox domain, metazoa, protein family

1 reference

Homeobox, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

sequence-specific DNA binding

IDA

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

DNA-binding transcription activator activity, RNA polymerase II-specific

IDA

1 reference

14 February 2019

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

1 reference

14 February 2019

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

single-stranded RNA binding

1 reference

14 February 2019

The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

DNA-binding transcription factor activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

4 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

11 October 2018

DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

11 October 2018

Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

11 October 2018

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

cerebral cortex GABAergic interneuron differentiation

biological process

1 reference

14 February 2019

Origins of cortical interneuron subtypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

proximal/distal pattern formation

2 references

14 February 2019

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

regulation of transcription by RNA polymerase II

1 reference

11 October 2018

Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

negative regulation of transcription by RNA polymerase II

1 reference

11 October 2018

Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

branching morphogenesis of a nerve

1 reference

14 February 2019

Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

embryonic skeletal system development

2 references

14 February 2019

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

odontogenesis of dentin-containing tooth

1 reference

14 February 2019

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

cerebral cortex GABAergic interneuron fate commitment

1 reference

14 February 2019

Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain

cartilage development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

forebrain neuron differentiation

1 reference

14 February 2019

Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

embryonic cranial skeleton morphogenesis

1 reference

14 February 2019

Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

olfactory bulb development

1 reference

14 February 2019

Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants

subpallium development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

negative regulation of Notch signaling pathway

1 reference

14 February 2019

Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

positive regulation of transcription by RNA polymerase II

2 references

11 October 2018

The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

11 October 2018

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

transcription by RNA polymerase II

IDA

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

positive regulation of cell differentiation

1 reference

14 February 2019

Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

negative regulation of photoreceptor cell differentiation

1 reference

14 February 2019

Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

positive regulation of amacrine cell differentiation

1 reference

14 February 2019

Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40764&geneProductId=UniProtKB:P40764

regulation of transcription by RNA polymerase II

3 references

14 February 2019

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40764

Distal-less-like homeobox protein, N-terminal domain

has part(s)

1 reference

Homeobox domain

1 reference

Homeobox, conserved site

1 reference

Homeobox domain, metazoa

1 reference

Helix-turn-helix motif

1 reference