Spleen focus forming virus (SFFV) proviral integration oncogene (Q21981396)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17433

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17433

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

RNA polymerase II cis-regulatory region sequence-specific DNA binding

5 references

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

24 April 2018

Transcriptional regulation of CD1D1 by Ets family transcription factors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

24 April 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

24 April 2018

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

24 April 2018

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

3 references

14 February 2019

14 February 2019

GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

DNA-binding transcription factor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

10 September 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

10 September 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

1 reference

10 September 2018

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

DNA-binding transcription repressor activity, RNA polymerase II-specific

protein binding

5 references

14 February 2019

Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

MOZ is essential for maintenance of hematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

RNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

1 reference

14 February 2019

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

10 September 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

sequence-specific DNA binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Pruning of the adipocyte peroxisome proliferator-activated receptor γ cistrome by hematopoietic master regulator PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

RNA polymerase II cis-regulatory region sequence-specific DNA binding

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

5 June 2018

Transcriptional regulation of CD1D1 by Ets family transcription factors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

5 June 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

5 June 2018

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

5 June 2018

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

RNA polymerase II cis-regulatory region sequence-specific DNA binding

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Transcriptional regulation of CD1D1 by Ets family transcription factors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

DNA-binding transcription factor activity, RNA polymerase II-specific

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

transcription factor binding

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

transcription regulator complex

cell component

IC

1 reference

7 November 2018

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

IC

nucleus

7 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

nucleoplasm

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

transcription regulator complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

myeloid leukocyte differentiation

IC

biological process

1 reference

14 February 2019

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

3 references

14 February 2019

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

cellular response to ethanol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

somatic stem cell population maintenance

1 reference

14 February 2019

A functional screen to identify novel effectors of hematopoietic stem cell activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

lymphocyte differentiation

1 reference

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

regulation of transcription by RNA polymerase II

2 references

21 June 2018

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

21 June 2018

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

myeloid dendritic cell differentiation

1 reference

14 February 2019

PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Transcriptional regulation of CD1D1 by Ets family transcription factors

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

negative regulation of MHC class II biosynthetic process

1 reference

14 February 2019

Repression of I-Aβ Gene Expression by the Transcription Factor PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

lymphoid progenitor cell differentiation

1 reference

14 February 2019

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

1 reference

21 June 2018

macrophage differentiation

1 reference

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

anatomical structure regression

1 reference

14 February 2019

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

positive regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Cathepsin E: a novel target for regulation by class II transactivator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

vasculature development

1 reference

14 February 2019

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

granulocyte differentiation

1 reference

14 February 2019

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

apoptotic process involved in blood vessel morphogenesis

1 reference

14 February 2019

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

erythrocyte differentiation

1 reference

14 February 2019

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

positive regulation of transcription by RNA polymerase II

2 references

7 November 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

7 November 2018

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

regulation of transcription by RNA polymerase II

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

cell differentiation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

positive regulation of transcription by RNA polymerase II

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

14 January 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

14 January 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

interleukin-6-mediated signaling pathway

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17433&geneProductId=UniProtKB:P17433

positive regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

14 February 2019

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17433

1 reference

InterPro Release 71.0