Alpha-1B adrenergic receptor (Q21982979)

http://www.ebi.ac.uk/interpro/protein/P97717

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

10 August 2016

1 reference

10 August 2016

signal transducer activity

English

molecular function

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

adrenergic receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

alpha1-adrenergic receptor activity

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

24 April 2018

Characterization of the hepatic alpha 1B-adrenoceptors of rats, mice and hamsters

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

alpha1-adrenergic receptor activity

IDA

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

Characterization of the hepatic alpha 1B-adrenoceptors of rats, mice and hamsters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

integral component of membrane

cell component

3 references

integral component of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

regulation of muscle contraction

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

A behavioral study of alpha-1b adrenergic receptor knockout mice: increased reaction to novelty and selectively reduced learning capacities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

A behavioral study of alpha-1b adrenergic receptor knockout mice: increased reaction to novelty and selectively reduced learning capacities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

24 April 2018

Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

behavioral response to cocaine

1 reference

8 April 2019

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

adult heart development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97717&geneProductId=UniProtKB:P97717

vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure

1 reference

8 April 2019

Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

negative regulation of Rho protein signal transduction

1 reference

8 April 2019

MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

negative regulation of glycogen catabolic process

1 reference

8 April 2019

Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

positive regulation of heart rate by epinephrine-norepinephrine

1 reference

8 April 2019

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

adenylate cyclase-activating adrenergic receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

phospholipase C-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

Gene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodeling

blood vessel remodeling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

positive regulation of glycogen catabolic process

1 reference

8 April 2019

Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

positive regulation of vasoconstriction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

positive regulation of the force of heart contraction by epinephrine-norepinephrine

1 reference

8 April 2019

Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

regulation of cardiac muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

positive regulation of smooth muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

cell growth involved in cardiac muscle cell development

1 reference

8 April 2019

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

response to steroid hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

neuron-glial cell signaling

1 reference

8 April 2019

Neuron-glia signaling via alpha(1) adrenoceptor-mediated Ca(2+) release in Bergmann glial cells in situ.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97717

physically interacts with

1 reference

5884

17 August 2016

1 reference

3342

17 August 2016

1 reference

8896

17 August 2016

1 reference

506

GPCR, rhodopsin-like, 7TM

English

retrieved

17 August 2016

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P97717

Identifiers

1 reference

10 August 2016