Platelet derived growth factor receptor, beta polypeptide (Q21983261)

Protein kinase-like domain superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

Platelet-derived growth factor receptor beta

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, receptor class III, conserved site, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

Immunoglobulin domain, protein family

1 reference

vascular endothelial growth factor binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

2 references

protein kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

8 references

14 February 2019

PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Packing contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

β1 integrins regulate fibroblast chemotaxis through control of N-WASP stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Identification of protein tyrosine phosphatases associating with the PDGF receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

protein tyrosine kinase activity

IPI

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor beta-receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

signal transducer activity

1 reference

24 April 2018

Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor-activated receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

phosphatidylinositol 3-kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

receptor tyrosine kinase

3 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

transmembrane signaling receptor activity

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

platelet-derived growth factor beta-receptor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor binding

3 references

14 February 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

transmembrane receptor protein tyrosine kinase activity

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

intrinsic component of plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

intracellular membrane-bounded organelle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

2 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

3 references

apical plasma membrane

2 references

5 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

metanephric glomerular mesangium development

biological process

1 reference

14 February 2019

Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of MAP kinase activity

IEP

1 reference

14 February 2019

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of phospholipase C activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cell migration involved in vasculogenesis

1 reference

14 February 2019

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cardiac myofibril assembly

1 reference

14 February 2019

The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of smooth muscle cell migration

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

protein phosphorylation

1 reference

14 February 2019

positive regulation of phosphoprotein phosphatase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of reactive oxygen species metabolic process

1 reference

14 February 2019

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

metanephric glomerular mesangial cell proliferation involved in metanephros development

IEP

1 reference

14 February 2019

Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of ERK1 and ERK2 cascade

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

24 April 2018

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

24 April 2018

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

smooth muscle tissue development

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

2 references

positive regulation of mitotic nuclear division

1 reference

14 February 2019

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor receptor-beta signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

phosphatidylinositol metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

embryonic organ development

1 reference

14 February 2019

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

transmembrane receptor protein tyrosine kinase signaling pathway

IEP

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

in utero embryonic development

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cell migration involved in coronary angiogenesis

1 reference

14 February 2019

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

nitrogen compound metabolic process

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of chemotaxis

1 reference

14 February 2019

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of DNA biosynthetic process

1 reference

14 February 2019

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

protein autophosphorylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

platelet-derived growth factor receptor signaling pathway

positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

1 reference

14 February 2019

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

regulation of actin cytoskeleton organization

1 reference

14 February 2019

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

retina vasculature development in camera-type eye

skeletal system morphogenesis

1 reference

14 February 2019

PDGF signaling specificity is mediated through multiple immediate early genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

phosphatidylinositol-mediated signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

smooth muscle cell chemotaxis

1 reference

14 February 2019

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cardiac vascular smooth muscle cell differentiation

1 reference

14 February 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

adrenal gland development

TAS

1 reference

14 February 2019

The PDGF signaling pathway controls multiple steroid-producing lineages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

metanephric glomerular capillary formation

1 reference

14 February 2019

The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of calcium ion import

1 reference

14 February 2019

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of cell population proliferation

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

14 February 2019

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

peptidyl-tyrosine phosphorylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

glycosaminoglycan biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of collagen biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of Rho protein signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

intracellular signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

metanephric mesenchymal cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cellular response to platelet-derived growth factor stimulus

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

negative regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of fibroblast proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of hepatic stellate cell activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

negative regulation of signal transduction

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05622&geneProductId=UniProtKB:P05622

positive regulation of ERK1 and ERK2 cascade

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

hematopoietic progenitor cell differentiation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of smooth muscle cell migration

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

positive regulation of MAPK cascade

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

cellular response to hydrogen peroxide

1 reference

14 February 2019

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

1 reference

14 February 2019

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05622

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5711

language of work or name

English

retrieved

17 August 2016

has part(s)

immunoglobulin subtype

1 reference

tyrosine-protein kinase, receptor class III, conserved site

1 reference

immunoglobulin domain

1 reference

immunoglobulin subtype 2

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

immunoglobulin-like domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference