Sphingosine kinase 2 (Q21983285)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JIA7

NAD kinase/diacylglycerol kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JIA7

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Diacylglycerol kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

D-erythro-sphingosine kinase activity

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

IMP

14 February 2019

The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

ATP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

protein binding

IPI

1 reference

14 February 2019

IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

IPI

NAD+ kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

cell component

cytosol

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

membrane

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

14 February 2019

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

lysosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

lysosomal membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

biological process

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

1 reference

14 February 2019

sphinganine-1-phosphate biosynthetic process

1 reference

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

female pregnancy

Ensembl genome database project

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

sphingosine metabolic process

IMP

1 reference

14 February 2019

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

negative regulation of apoptotic process

IMP

1 reference

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

brain development

1 reference

14 February 2019

Essential role for sphingosine kinases in neural and vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

blood vessel development

1 reference

14 February 2019

Essential role for sphingosine kinases in neural and vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

positive regulation of cell population proliferation

1 reference

14 February 2019

Essential role for sphingosine kinases in neural and vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

cell population proliferation

1 reference

14 February 2019

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

lipid phosphorylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

sphingosine-1-phosphate receptor signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIA7

metabolism

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JIA7&geneProductId=UniProtKB:Q9JIA7

1 reference

27 March 2018

Diacylglycerol kinase, catalytic domain

has part(s)

1 reference

InterPro Release 71.0