Interferon regulatory factor 4 (Q21984131)

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mammalian protein found in Mus musculus

PU.1 interaction partner
lymphocyte-specific interferon regulatory factor
LSIRF
interferon regulatory factor 4
Sfpi1/PU.1 interaction partner
NF-EM5
Irf4
transcriptional activator PIP

Language	Label	Description	Also known as
English	Interferon regulatory factor 4	mammalian protein found in Mus musculus	PU.1 interaction partner lymphocyte-specific interferon regulatory factor LSIRF interferon regulatory factor 4 Sfpi1/PU.1 interaction partner NF-EM5 Irf4 transcriptional activator PIP

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

SMAD-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

SMAD/FHA domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

Interferon regulatory factors

1 reference

based on heuristic

inferred from protein domain or family

Interferon regulatory factor-3, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

sequence-specific DNA binding

determination method

3 references

14 February 2019

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Compensatory dendritic cell development mediated by BATF-IRF interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

BATF-JUN is critical for IRF4-mediated transcription in T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

DNA-binding transcription factor activity

determination method

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Compensatory dendritic cell development mediated by BATF-IRF interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

BATF-JUN is critical for IRF4-mediated transcription in T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method

4 references

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

protein-lysine N-methyltransferase activity

determination method

1 reference

1 January 2018

Lysine methylation of VCP by a member of a novel human protein methyltransferase family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

protein binding

determination method

7 references

14 February 2019

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Compensatory dendritic cell development mediated by BATF-IRF interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

BATF-JUN is critical for IRF4-mediated transcription in T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Negative regulation of Toll-like-receptor signaling by IRF-4.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

IRF4 is a key thermogenic transcriptional partner of PGC-1α

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

A validated regulatory network for Th17 cell specification

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

transcription, DNA-templated

determination method

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

T-helper 17 cell lineage commitment

determination method

1 reference

14 February 2019

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

positive regulation of transcription, DNA-templated

determination method

3 references

negative regulation of toll-like receptor signaling pathway

determination method

1 reference

14 February 2019

Negative regulation of Toll-like-receptor signaling by IRF-4.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

histone H3 acetylation

determination method

1 reference

14 February 2019

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

histone H4 acetylation

determination method

1 reference

14 February 2019

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

positive regulation of DNA binding

determination method

1 reference

14 February 2019

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

defense response to protozoan

determination method

1 reference

14 February 2019

Compensatory dendritic cell development mediated by BATF-IRF interactions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

protein methylation

determination method

1 reference

1 January 2018

Lysine methylation of VCP by a member of a novel human protein methyltransferase family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

peptidyl-lysine methylation

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

transcription by RNA polymerase II

determination method

1 reference

31 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64287&geneProductId=UniProtKB:Q64287

determination method

positive regulation of cold-induced thermogenesis

determination method

1 reference

14 February 2019

IRF4 is a key thermogenic transcriptional partner of PGC-1α

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

immune system process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64287

determination method

Interferon regulatory factor DNA-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

Interferon regulatory factor, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

Interferon regulatory factor-3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q64287

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000021784

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000021784

ENSMUSP00000105936

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105936

ENSMUSP00000152134

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000152134

PDB structure ID

1 reference

UniProt protein ID

10 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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