Fyn proto-oncogene (Q21984751)

Protein kinase-like domain superfamily

1 reference

SH2 domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

Fyn/Yrk, SH3 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

transmembrane transporter binding

1 reference

14 February 2019

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

2 references

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

23 references

14 February 2019

HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Molecular cloning of Fyn-associated molecules in the mouse central nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

'Srcasm: a novel Src activating and signaling molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Bioinformatics and cellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

G protein-coupled receptor binding

IPI

1 reference

14 February 2019

GPRC5B activates obesity-associated inflammatory signaling in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

2 references

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

signaling receptor binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

peptide hormone receptor binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

T cell receptor binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

phosphatidylinositol 3-kinase binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

protein kinase activity

protein-containing complex binding

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

protein tyrosine kinase activity

13 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 January 2018

Regulation of Ly49D/DAP12 signal transduction by Src-family kinases and CD45

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

EXP

protein kinase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

signaling receptor binding

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

alpha-tubulin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

protein tyrosine kinase activity

IPI

12 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

extrinsic component of cytoplasmic side of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 reference

14 February 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

intracellular membrane-bounded organelle

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 reference

14 February 2019

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

3 references

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

3 references

1 reference

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

glial cell projection

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

regulation of apoptotic process

biological process

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

cellular response to transforming growth factor beta stimulus

1 reference

14 February 2019

Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

activated T cell proliferation

1 reference

14 February 2019

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

adaptive immune response

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

negative regulation of protein catabolic process

1 reference

14 February 2019

Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

immune system process

1 reference

14 February 2019

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

dendrite morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

cellular response to growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

cellular response to platelet-derived growth factor stimulus

1 reference

14 February 2019

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

negative regulation of gene expression

1 reference

14 February 2019

CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

negative regulation of protein ubiquitination

1 reference

14 February 2019

Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

protein phosphorylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

cell surface receptor signaling pathway

1 reference

14 February 2019

Mouse CD24 as a signaling molecule for integrin-mediated cell binding: functional and physical association with src-kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

cellular response to peptide hormone stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

regulation of cell population proliferation

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

regulation of cell shape

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

positive regulation of neuron projection development

1 reference

14 February 2019

Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

peptidyl-tyrosine autophosphorylation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

GPRC5B activates obesity-associated inflammatory signaling in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

1 reference

14 February 2019

Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

peptidyl-tyrosine phosphorylation

TAS

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

14 February 2019

CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

innate immune response

1 reference

31 January 2017

1 reference

14 February 2019

Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

T cell receptor signaling pathway

3 references

positive regulation of protein localization to nucleus

detection of mechanical stimulus involved in sensory perception of pain

1 reference

14 February 2019

Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

ephrin receptor signaling pathway

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

TAS

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

negative regulation of neuron apoptotic process

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

1 reference

31 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P39688

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

14 February 2019

Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

protein autophosphorylation

3 references

regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

positive regulation of protein targeting to membrane

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

regulation of glutamate receptor signaling pathway

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

positive regulation of neuron death

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

negative regulation of dendritic spine maintenance

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

response to amyloid-beta

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

regulation of calcium ion import across plasma membrane

1 reference

14 February 2019

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39688

cellular response to amyloid-beta

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39688&geneProductId=UniProtKB:P39688

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, active site

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

SH3 domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

Fyn/Yrk, SH3 domain

1 reference