Glutamate-cysteine ligase, modifier subunit (Q21985413)

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mammalian protein found in Mus musculus
  • glutamate--cysteine ligase regulatory subunit
  • gamma-glutamylcysteine synthetase regulatory subunit
  • gamma-ECS regulatory subunit
  • Glutamate--cysteine ligase modifier subunit
  • Gclm
  • GCS light chain
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Language Label Description Also known as
English
Glutamate-cysteine ligase, modifier subunit
mammalian protein found in Mus musculus
  • glutamate--cysteine ligase regulatory subunit
  • gamma-glutamylcysteine synthetase regulatory subunit
  • gamma-ECS regulatory subunit
  • Glutamate--cysteine ligase modifier subunit
  • Gclm
  • GCS light chain

Statements

molecular function
cell component
biological process
positive regulation of glutamate-cysteine ligase activity
determination method or standard
IDA
IEA
ISO
5 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O09172&geneProductId=UniProtKB:O09172
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O09172&geneProductId=UniProtKB:O09172
determination method or standard
IEA
retrieved
24 April 2018
stated in
Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O09172&geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
24 April 2018
stated in
Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O09172&geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
24 April 2018
stated in
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O09172&geneProductId=UniProtKB:O09172
determination method or standard
IDA
glutathione biosynthetic process
determination method or standard
IBA
IDA
IEA
ISO
ISS
7 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O09172
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O09172
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IEA
retrieved
14 February 2019
stated in
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IBA
positive regulation of glutamate-cysteine ligase activity
determination method or standard
IBA
IDA
IEA
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IEA
retrieved
14 February 2019
stated in
Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
14 February 2019
stated in
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
14 February 2019
stated in
Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O09172
determination method or standard
IBA

Identifiers

 
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