Immunoglobulin (CD79A) binding protein 1 (Q21985506)

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mammalian protein found in Mus musculus

Igbp1
alpha 4
p52
protein phosphatase 2/4/6 regulatory subunit
alpha4 phosphoprotein
CD79a-binding protein 1
lymphocyte signal transduction molecule alpha 4
phosphoprotein, component, 52 kDa
immunoglobulin-binding protein 1

Language	Label	Description	Also known as
English	Immunoglobulin (CD79A) binding protein 1	mammalian protein found in Mus musculus	Igbp1 alpha 4 p52 protein phosphatase 2/4/6 regulatory subunit alpha4 phosphoprotein CD79a-binding protein 1 lymphocyte signal transduction molecule alpha 4 phosphoprotein, component, 52 kDa immunoglobulin-binding protein 1

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

TAP46-like protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61249

TAP42/TAP46-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61249

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein domain specific binding

determination method

1 reference

14 February 2019

MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

protein binding

determination method

3 references

14 February 2019

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

14 February 2019

Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

14 February 2019

Alpha4 is an essential regulator of PP2A phosphatase activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

mitogen-activated protein kinase kinase binding

determination method

1 reference

14 February 2019

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

protein phosphatase 2A binding

determination method

3 references

protein phosphatase regulator activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

determination method

determination method

1 reference

14 February 2019

MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

biological process

negative regulation of protein dephosphorylation

determination method

2 references

negative regulation of apoptotic signaling pathway

determination method

1 reference

14 February 2019

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

B cell activation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

positive regulation of dephosphorylation

determination method

1 reference

14 February 2019

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

regulation of signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

negative regulation of stress-activated MAPK cascade

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

response to tumor necrosis factor

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

regulation of microtubule-based movement

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

response to interleukin-1

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

regulation of phosphoprotein phosphatase activity

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61249

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000033570

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000033570

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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