Purinergic receptor P2X, ligand-gated ion channel, 2 (Q21985923)

http://www.ebi.ac.uk/interpro/protein/Q8K3P1

P2X2 purinoceptor

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K3P1

1 reference

25 May 2022

1 reference

25 May 2022

transcription coactivator activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

extracellularly ATP-gated cation channel activity

ISS

6 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

5 June 2018

Identification of P2X receptors in cultured mouse and rat parasympathetic otic ganglion neurones including P2X knockout studies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

5 June 2018

Identification of P2X receptors in cultured mouse and rat parasympathetic otic ganglion neurones including P2X knockout studies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

5 June 2018

ATP modulation of excitatory synapses onto interneurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

ligand-gated ion channel activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

nickel cation binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

phosphatidylinositol binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

extracellularly ATP-gated cation channel activity

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

Identification of P2X receptors in cultured mouse and rat parasympathetic otic ganglion neurones including P2X knockout studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

Identification of P2X receptors in cultured mouse and rat parasympathetic otic ganglion neurones including P2X knockout studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

ATP modulation of excitatory synapses onto interneurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

ATP-gated ion channel activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

integral component of nuclear inner membrane

cell component

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

integral component of plasma membrane

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

intracellular anatomical structure

1 reference

10 September 2018

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K3P1&geneProductId=UniProtKB:Q8K3P1

IDA

apical plasma membrane

3 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

Abnormalities in neuromuscular junction structure and skeletal muscle function in mice lacking the P2X2 nucleotide receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

integral component of membrane

3 references

glutamatergic synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

integral component of presynaptic active zone membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

4 references

14 February 2019

Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

urinary bladder smooth muscle contraction

2 references

2 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

response to organic substance

1 reference

14 February 2019

P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

cation transmembrane transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

neuromuscular synaptic transmission

1 reference

14 February 2019

P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

behavioral response to pain

IGI

neuromuscular junction development

2 references

1 reference

14 February 2019

Abnormalities in neuromuscular junction structure and skeletal muscle function in mice lacking the P2X2 nucleotide receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

skeletal muscle fiber development

1 reference

14 February 2019

Abnormalities in neuromuscular junction structure and skeletal muscle function in mice lacking the P2X2 nucleotide receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

detection of hypoxic conditions in blood by carotid body chemoreceptor signaling

1 reference

14 February 2019

Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

ATP signaling is crucial for communication from taste buds to gustatory nerves

response to carbohydrate

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

sensory perception of taste

1 reference

14 February 2019

ATP signaling is crucial for communication from taste buds to gustatory nerves

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

chemical synaptic transmission

IGI

1 reference

14 February 2019

ATP modulation of excitatory synapses onto interneurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

purinergic nucleotide receptor signaling pathway

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

excitatory postsynaptic potential

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

neuronal action potential

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

protein heterooligomerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

positive regulation of nucleic acid-templated transcription

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

ion transmembrane transport

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

regulation of presynaptic cytosolic calcium ion concentration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1

regulation of synaptic vesicle exocytosis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K3P1