Interferon regulatory factor 8 (Q21986019)

SMAD-like domain superfamily

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

SMAD/FHA domain superfamily

1 reference

Interferon regulatory factors

1 reference

based on heuristic

inferred from protein domain or family

Interferon regulatory factor-3, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

Compensatory dendritic cell development mediated by BATF-IRF interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

RNA polymerase II transcription regulatory region sequence-specific DNA binding

IPI

1 reference

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

DNA-binding transcription repressor activity, RNA polymerase II-specific

IDA

4 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

DNA-binding transcription factor activity, RNA polymerase II-specific

IEA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

5 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

7 November 2018

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

7 November 2018

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

defense response to protozoan

IBA

biological process

1 reference

14 February 2019

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

myeloid cell differentiation

IPI

1 reference

14 February 2019

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

positive regulation of interferon-gamma production

1 reference

14 February 2019

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

cellular response to lipopolysaccharide

1 reference

14 February 2019

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

defense response to bacterium

1 reference

14 February 2019

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

response to bacterium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

positive regulation of transcription initiation from RNA polymerase II promoter

1 reference

16 July 2018

The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

positive regulation of interleukin-12 production

IDA

1 reference

14 February 2019

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

1 reference

14 February 2019

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23611&geneProductId=UniProtKB:P23611

1 reference

14 February 2019

Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

negative regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

Interferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCOR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

cellular response to interferon-gamma

IEA

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IEA

immune system process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23611

Interferon regulatory factor DNA-binding domain

IBA

has part(s)

1 reference

Interferon regulatory factor, conserved site

1 reference

Interferon regulatory factor-3

1 reference