LIM domain binding 1 (Q21986054)

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mammalian protein found in Mus musculus
  • CLIM-2
  • LDB-1
  • LIM domain-binding factor CLIM2
  • mLdb1
  • carboxyl-terminal LIM domain-binding protein 2
  • nuclear LIM interactor
  • LIM domain-binding protein 1
  • Ldb1
edit
Language Label Description Also known as
English
LIM domain binding 1
mammalian protein found in Mus musculus
  • CLIM-2
  • LDB-1
  • LIM domain-binding factor CLIM2
  • mLdb1
  • carboxyl-terminal LIM domain-binding protein 2
  • nuclear LIM interactor
  • LIM domain-binding protein 1
  • Ldb1

Statements

molecular function
LIM domain binding
determination method
ISO
IDA
IEA
IPI
7 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
16 July 2018
stated in
Interactions between LIM domains and the LIM domain-binding protein Ldb1
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
16 July 2018
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
16 July 2018
stated in
Functional analysis of the nuclear LIM domain interactor NLI
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IDA
protein binding
determination method
IPI
11 references
retrieved
14 February 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
14 February 2019
stated in
A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
LIM domain binding
determination method
IBA
IDA
IEA
IPI
ISO
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
9 May 2019
stated in
Interactions between LIM domains and the LIM domain-binding protein Ldb1
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
Functional analysis of the nuclear LIM domain interactor NLI
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
9 May 2019
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IBA
protein binding
determination method
IPI
TAS
12 references
retrieved
9 May 2019
stated in
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
TAS
retrieved
9 May 2019
stated in
A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
retrieved
9 May 2019
stated in
A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
ISO
7 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
16 July 2018
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
16 July 2018
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
16 July 2018
stated in
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
ISO
8 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
9 May 2019
stated in
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation
GOA
curator
UniProt
UniProt protein ID
P70662
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
9 May 2019
stated in
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IGI
IEA
IMP
ISO
8 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IMP
retrieved
16 July 2018
stated in
Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IMP
retrieved
16 July 2018
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
16 July 2018
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
16 July 2018
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
16 July 2018
stated in
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70662&geneProductId=UniProtKB:P70662
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IEA
IGI
IMP
ISO
9 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
ISO
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IMP
retrieved
9 May 2019
stated in
Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IMP
retrieved
9 May 2019
stated in
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
9 May 2019
stated in
Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
9 May 2019
stated in
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
9 May 2019
stated in
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70662
determination method
IBA

Identifiers

 
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