Spalt like transcription factor 4 (Q21987732)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8BX22

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

1 reference

14 February 2019

sequence-specific DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

1 reference

14 February 2019

protein binding

6 references

14 February 2019

Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

An Oct4-centered protein interaction network in embryonic stem cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

1 reference

14 February 2019

transcription factor binding

1 reference

14 February 2019

Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

1 reference

14 February 2019

transcription regulator complex

IC

1 reference

14 February 2019

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

IC

heterochromatin

1 reference

14 February 2019

Mouse homolog of SALL1, a causative gene for Townes-Brocks syndrome, binds to A/T-rich sequences in pericentric heterochromatin via its C-terminal zinc finger domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

protein-containing complex

1 reference

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

3 references

14 February 2019

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

regulation of transcription, DNA-templated

biological process

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

ventricular septum development

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

in utero embryonic development

1 reference

14 February 2019

Murine inner cell mass-derived lineages depend on Sall4 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

inner cell mass cell proliferation

1 reference

14 February 2019

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

stem cell population maintenance

1 reference

14 February 2019

Mediator and cohesin connect gene expression and chromatin architecture

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

heart development

1 reference

14 February 2019

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

neural tube closure

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

14 February 2019

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

embryonic limb morphogenesis

neural tube development

1 reference

14 February 2019

Sall1, sall2, and sall4 are required for neural tube closure in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

tissue development

1 reference

14 February 2019

Murine inner cell mass-derived lineages depend on Sall4 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

positive regulation of transcription by RNA polymerase II

neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8BX22&geneProductId=UniProtKB:Q8BX22

1 reference

27 March 2018

regulation of transcription, DNA-templated

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8BX22

has part(s)

Zinc finger C2H2-type

1 reference

InterPro Release 71.0