Core binding factor beta (Q21987847)

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mammalian protein found in Mus musculus

PEA2-beta
core-binding factor subunit beta
PEBP2-beta
SL3/AKV core-binding factor beta subunit
Cbfb
SL3-3 enhancer factor 1 subunit beta
polyomavirus enhancer-binding protein 2 beta subunit
CBF-beta

Language	Label	Description	Also known as
English	Core binding factor beta	mammalian protein found in Mus musculus	PEA2-beta core-binding factor subunit beta PEBP2-beta SL3/AKV core-binding factor beta subunit Cbfb SL3-3 enhancer factor 1 subunit beta polyomavirus enhancer-binding protein 2 beta subunit CBF-beta

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Core-binding factor, beta subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08024

Core-binding factor, beta subunit superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08024

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transcription coactivator activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

protein binding

determination method

1 reference

14 February 2019

Cloning and expression pattern of a novel PEBP2 beta-binding protein (charged amino acid rich leucine zipper-1[Crl-1]) in the mouse

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

sequence-specific DNA binding

determination method

1 reference

24 April 2018

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

determination method

3 references

transcription coregulator activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

determination method

3 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

24 April 2018

Cbfbeta interacts with Runx2 and has a critical role in bone development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

protein-containing complex

determination method

1 reference

14 February 2019

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

core-binding factor complex

determination method

1 reference

10 September 2018

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08024&geneProductId=UniProtKB:Q08024

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

14 February 2019

Cbfbeta interacts with Runx2 and has a critical role in bone development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

biological process

definitive hemopoiesis

determination method

1 reference

14 February 2019

Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

myeloid cell differentiation

determination method

1 reference

14 February 2019

The core-binding factor beta subunit is required for bone formation and hematopoietic maturation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

cell maturation

determination method

1 reference

14 February 2019

Cbfbeta interacts with Runx2 and has a critical role in bone development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

osteoblast differentiation

determination method

1 reference

14 February 2019

Cbfbeta interacts with Runx2 and has a critical role in bone development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Cbfbeta interacts with Runx2 and has a critical role in bone development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

lymphocyte differentiation

determination method

1 reference

14 February 2019

The core-binding factor beta subunit is required for bone formation and hematopoietic maturation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

negative regulation of CD4-positive, alpha-beta T cell differentiation

determination method

1 reference

14 February 2019

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

positive regulation of CD8-positive, alpha-beta T cell differentiation

determination method

1 reference

14 February 2019

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08024

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000059382

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000059382

ENSMUSP00000105019

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105019

ENSMUSP00000105022

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105022

ENSMUSP00000105021

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105021

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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