SRY (sex determining region Y)-box 9 (Q21990154)

High mobility group box domain superfamily

1 reference

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sox developmental protein N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

11 October 2018

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

core promoter sequence-specific DNA binding

1 reference

14 February 2019

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

pre-mRNA intronic binding

IPI

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

3 references

6 references

14 February 2019

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

sequence-specific DNA binding

IPI

1 reference

14 February 2019

The homeobox transcription factor Barx2 regulates chondrogenesis during limb development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

16 July 2018

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

protein heterodimerization activity

1 reference

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

3 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

cis-regulatory region sequence-specific DNA binding

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

protein kinase activity

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

transcription cis-regulatory region binding

1 reference

14 February 2019

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

core promoter sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISO

3 references

DNA-binding transcription activator activity, RNA polymerase II-specific

DNA-binding transcription factor activity, RNA polymerase II-specific

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

DNA-binding transcription activator activity, RNA polymerase II-specific

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

27 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Expression of p63 in the mouse primordial germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Foxl2 is required for commitment to ovary differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Distribution of the transcription factors Sox9, AP-2, and [delta]EF1 in adult murine articular and meniscal cartilage and growth plate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox15 is up regulated in the embryonic mouse testis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Homozygous inactivation of Sox9 causes complete XY sex reversal in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

protein-containing complex

3 references

transcription regulator complex

skeletal system development

3 references

bronchus cartilage development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of protein catabolic process

1 reference

14 February 2019

Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Loss of Sox9 function results in defective chondrocyte differentiation of mouse embryonic stem cells in vitro

chondrocyte development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of cell proliferation involved in heart morphogenesis

1 reference

14 February 2019

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

oligodendrocyte differentiation

1 reference

16 July 2018

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

lung smooth muscle development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

mammary gland development

1 reference

14 February 2019

RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of photoreceptor cell differentiation

1 reference

14 February 2019

The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Müller glial cell development in mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

intrahepatic bile duct development

1 reference

14 February 2019

Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of cell adhesion

1 reference

14 February 2019

Sox9 is required for invagination of the otic placode in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of chondrocyte differentiation

1 reference

14 February 2019

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of mesenchymal cell proliferation

astrocyte fate commitment

2 references

1 reference

14 February 2019

The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Müller glial cell development in mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of chondrocyte differentiation

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

prostate gland morphogenesis

1 reference

14 February 2019

Sox9 is required for prostate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of epithelial cell proliferation

1 reference

14 February 2019

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

lung epithelial cell differentiation

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

chondrocyte differentiation involved in endochondral bone morphogenesis

3 references

endocrine pancreas development

1 reference

14 February 2019

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of cell population proliferation

1 reference

14 February 2019

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to transforming growth factor beta stimulus

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of mesenchymal cell apoptotic process

1 reference

14 February 2019

Lung epithelial branching program antagonizes alveolar differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

3 references

1 reference

14 February 2019

Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of myoblast differentiation

1 reference

14 February 2019

Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of cell proliferation involved in tissue homeostasis

1 reference

14 February 2019

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

ureter smooth muscle cell differentiation

1 reference

14 February 2019

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

notochord development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of epithelial cell migration

4 references

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Sertoli cell differentiation

1 reference

14 February 2019

Functional analysis of Sox8 and Sox9 during sex determination in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

male sex determination

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of gene expression

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

metanephric nephron tubule formation

1 reference

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of transcription, DNA-templated

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

16 July 2018

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

regulation of branching involved in lung morphogenesis

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

central nervous system development

1 reference

16 July 2018

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia

cartilage development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Harderian gland development

1 reference

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

A male-specific role for SOX9 in vertebrate sex determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

ureter urothelium development

1 reference

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

heart valve formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of cartilage development

3 references

metanephric tubule development

1 reference

14 February 2019

A male-specific role for SOX9 in vertebrate sex determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

endochondral bone morphogenesis

1 reference

14 February 2019

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

trachea cartilage development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

lacrimal gland development

1 reference

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning

Notch signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

hair follicle development

1 reference

14 February 2019

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of cell cycle process

3 references

male gonad development

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Functional analysis of Sox8 and Sox9 during sex determination in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 induces testis development in XX transgenic mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Functional analysis of Sox8 and Sox9 during sex determination in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A male-specific role for SOX9 in vertebrate sex determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

The Sox9 transcription factor determines glial fate choice in the developing spinal cord

cell fate specification

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

intestinal epithelial structure maintenance

1 reference

14 February 2019

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of extracellular matrix assembly

1 reference

14 February 2019

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of apoptotic process

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 is required for maintenance of the pancreatic progenitor cell pool

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of mesenchymal stem cell differentiation

3 references

retina development in camera-type eye

1 reference

14 February 2019

The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Müller glial cell development in mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to interleukin-1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

epithelial to mesenchymal transition

1 reference

14 February 2019

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

homeostasis of number of cells within a tissue

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of transcription, DNA-templated

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of male gonad development

cAMP-mediated signaling

3 references

3 references

3 references

negative regulation of bone mineralization

1 reference

14 February 2019

Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

morphogenesis of a branching epithelium

3 references

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

neural crest cell development

1 reference

14 February 2019

The transcriptional control of trunk neural crest induction, survival, and delamination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

somatic stem cell population maintenance

1 reference

14 February 2019

SOX9 induces and maintains neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Sox9 is required for invagination of the otic placode in mice

otic vesicle formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

otic vesicle development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

endocardial cushion morphogenesis

1 reference

14 February 2019

Reelin in the extracellular matrix and dendritic spines of the cortex and hippocampus: a comparison between wild type and heterozygous reeler mice by immunoelectron microscopy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of epithelial cell differentiation

1 reference

14 February 2019

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of epithelial cell proliferation involved in lung morphogenesis

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of cell population proliferation

1 reference

14 February 2019

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

heart valve morphogenesis

1 reference

14 February 2019

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cytoskeleton organization

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse

cochlea morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of cell population proliferation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 is required for maintenance of the pancreatic progenitor cell pool

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

epithelial cell proliferation involved in prostatic bud elongation

1 reference

14 February 2019

Sox9 is required for prostate development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

retinal rod cell differentiation

1 reference

14 February 2019

The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Müller glial cell development in mouse retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

protein localization to nucleus

1 reference

14 February 2019

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

regulation of cell differentiation

1 reference

14 February 2019

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of epithelial cell differentiation

1 reference

14 February 2019

Lung epithelial branching program antagonizes alveolar differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of transcription by RNA polymerase II

15 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Inhibitory role of Notch1 in calcific aortic valve disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

SOX9 directly regulates the type-II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

16 July 2018

The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

negative regulation of ossification

1 reference

14 February 2019

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to heparin

1 reference

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of biomineral tissue development

1 reference

24 April 2018

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

negative regulation of immune system process

1 reference

14 February 2019

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of canonical Wnt signaling pathway

3 references

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

14 February 2019

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to epidermal growth factor stimulus

1 reference

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

heart valve development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

protein kinase B signaling

1 reference

14 February 2019

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

chondrocyte hypertrophy

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of kidney development

1 reference

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to mechanical stimulus

1 reference

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

transcription by RNA polymerase II

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

SOX9 controls epithelial branching by activating RET effector genes during kidney development

renal vesicle induction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of epithelial cell proliferation

3 references

14 February 2019

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

SOX9 controls epithelial branching by activating RET effector genes during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

epidermal growth factor receptor signaling pathway

1 reference

14 February 2019

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer

ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

1 reference

14 February 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cartilage condensation

3 references

14 February 2019

14 February 2019

Sox9 is required for cartilage formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

neural crest cell fate specification

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

cellular response to BMP stimulus

ISS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

anterior head development

ISS

1 reference

14 February 2019

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

protein-containing complex assembly

3 references

positive regulation of gene expression

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

negative regulation of biomineral tissue development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

morphogenesis of an epithelium

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

chondrocyte differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of chondrocyte differentiation

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

positive regulation of transcription by RNA polymerase II

16 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Inhibitory role of Notch1 in calcific aortic valve disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX9 directly regulates the type-II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

aortic valve morphogenesis

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04887&geneProductId=UniProtKB:Q04887

regulation of gene expression

1 reference

14 February 2019

Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04887

Sox developmental protein N-terminal

has part(s)

1 reference

High mobility group box domain

1 reference