SRY (sex determining region Y)-box 10 (Q21990155)

http://www.ebi.ac.uk/interpro/protein/Q04888

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sox developmental protein N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

3 references

14 February 2019

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

IPI

1 reference

10 September 2018

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

DNA-binding transcription factor activity, RNA polymerase II-specific

identical protein binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

DNA-binding transcription factor activity

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

promoter-specific chromatin binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

DNA-binding transcription factor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

transcription factor binding

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

7 November 2018

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

transcription factor binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

extrinsic component of mitochondrial outer membrane

cell component

1 reference

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

mitochondrial outer membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

positive regulation of neuroblast proliferation

biological process

1 reference

14 February 2019

Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

1 reference

14 February 2019

Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

peripheral nervous system development

1 reference

24 April 2018

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

morphogenesis of a branching epithelium

IGI

IGI

oligodendrocyte differentiation

4 references

24 April 2018

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

negative regulation of apoptotic process

1 reference

14 February 2019

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

in utero embryonic development

1 reference

14 February 2019

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

enteric nervous system development

3 references

24 April 2018

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

Association of megacolon with a new dominant spotting gene (Dom) in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

1 reference

14 February 2019

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

neural crest cell migration

1 reference

24 April 2018

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

melanocyte differentiation

1 reference

14 February 2019

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

negative regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

lacrimal gland development

1 reference

14 February 2019

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

positive regulation of transcription by RNA polymerase II

5 references

24 April 2018

Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

digestive tract morphogenesis

3 references

14 February 2019

Association of megacolon with a new dominant spotting gene (Dom) in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

positive regulation of gliogenesis

IGI

1 reference

14 February 2019

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

oligodendrocyte development

central nervous system myelination

transcription elongation from RNA polymerase II promoter

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

negative regulation of Schwann cell proliferation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

positive regulation of gene expression

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

positive regulation of myelination

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

negative regulation of transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

positive regulation of transcription, DNA-templated

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

24 April 2018

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04888&geneProductId=UniProtKB:Q04888

morphogenesis of an epithelium

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

central nervous system development

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

positive regulation of transcription, DNA-templated

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

positive regulation of transcription by RNA polymerase II

6 references

14 February 2019

Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

enteric nervous system development

4 references

14 February 2019

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Association of megacolon with a new dominant spotting gene (Dom) in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

oligodendrocyte differentiation

5 references

14 February 2019

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

stem cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

cellular response to progesterone stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04888

Sox developmental protein N-terminal

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04888

High mobility group box domain

1 reference

stated in

InterPro Release 71.0