Smoothelin-like 1 (Q21990634)

http://www.ebi.ac.uk/interpro/protein/Q99LM3

Calponin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein phosphatase inhibitor activity

1 reference

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

protein phosphatase 1 binding

ISO

1 reference

16 July 2018

Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LM3&geneProductId=UniProtKB:Q99LM3

myosin phosphatase regulator activity

IPI

1 reference

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

1 reference

14 February 2019

Tropomyosin-binding properties of the CHASM protein are dependent upon its calponin homology domain

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

1 reference

16 July 2018

Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LM3&geneProductId=UniProtKB:Q99LM3

Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding

IPI

protein self-association

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

1 reference

14 February 2019

Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

disordered domain specific binding

IPI

1 reference

14 February 2019

Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

protein phosphatase 1 binding

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LM3&geneProductId=UniProtKB:Q99LM3

16 July 2018

Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LM3&geneProductId=UniProtKB:Q99LM3

16 July 2018

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99LM3&geneProductId=UniProtKB:Q99LM3

microtubule organizing center

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

negative regulation of transcription, DNA-templated

IBA

biological process

1 reference

14 February 2019

Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

1 reference

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

peptidyl-serine phosphorylation

IMP

1 reference

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

positive regulation of vasoconstriction

IDA

muscle organ morphogenesis

IMP

1 reference

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

negative regulation of phosphoprotein phosphatase activity

IMP

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

regulation of phosphoprotein phosphatase activity

IEA

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

actin cytoskeleton organization

IEA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

positive regulation of vasoconstriction

IBA

3 references

14 February 2019

Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99LM3

IBA

has part(s)

Calponin homology domain

1 reference

stated in

InterPro Release 71.0