Synaptonemal complex protein 3 (Q21990670)

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mammalian protein found in Mus musculus
  • SCP-3
  • synaptonemal complex protein 3
  • Sycp3
edit
Language Label Description Also known as
English
Synaptonemal complex protein 3
mammalian protein found in Mus musculus
  • SCP-3
  • synaptonemal complex protein 3
  • Sycp3

Statements

cell component
synaptonemal complex
determination method
IDA
ISO
17 references
retrieved
24 April 2018
stated in
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
ISO
retrieved
24 April 2018
stated in
Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
TOPAZ1, a germ cell specific factor, is essential for male meiotic progression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Deletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell loss
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
The mouse polyubiquitin gene Ubb is essential for meiotic progression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
The DNA methyltransferase DNMT3C protects male germ cells from transposon activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
24 April 2018
stated in
FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70281&geneProductId=UniProtKB:P70281
determination method
IDA
lateral element
determination method
IDA
ISO
13 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
ISO
retrieved
14 February 2019
stated in
The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility
GOA
curator
UniProt
UniProt protein ID
P70281
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Meiotic cohesin complexes are essential for the formation of the axial element in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Meikin is a conserved regulator of meiosis-I-specific kinetochore function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Disruption of CHTF18 causes defective meiotic recombination in male mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Sequential assembly of centromeric proteins in male mouse meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
synaptonemal complex
determination method
IBA
IDA
ISO
19 references
retrieved
14 February 2019
stated in
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
ISO
retrieved
14 February 2019
stated in
The DNA methyltransferase DNMT3C protects male germ cells from transposon activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Deletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell loss
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
TOPAZ1, a germ cell specific factor, is essential for male meiotic progression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
The mouse polyubiquitin gene Ubb is essential for meiotic progression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70281
determination method
IBA
biological process

Identifiers

 
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