Usherin (Q21992275)

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

Immunoglobulin-like fold

1 reference

Usherin

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Fibronectin type III, protein family

1 reference

Laminin G domain, protein family

1 reference

Laminin EGF domain, protein family

1 reference

LamG-like jellyroll fold, protein family

1 reference

Laminin, N-terminal domain, protein family

1 reference

protein homodimerization activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

5 references

9 May 2019

Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

integral component of membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

stereocilia ankle link complex

1 reference

9 May 2019

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells

stereocilia ankle link

3 references

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

apical plasma membrane

1 reference

9 May 2019

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

periciliary membrane compartment

3 references

9 May 2019

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

photoreceptor connecting cilium

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

14 February 2019

A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

14 February 2019

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q2QI47&geneProductId=UniProtKB:Q2QI47

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q2QI47&geneProductId=UniProtKB:Q2QI47

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

2 references

2 references

photoreceptor inner segment

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

photoreceptor connecting cilium

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

establishment of protein localization

1 reference

9 May 2019

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

hair cell differentiation

IMP

1 reference

9 May 2019

Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

inner ear receptor cell differentiation

IEP

1 reference

9 May 2019

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

photoreceptor cell maintenance

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

retina development in camera-type eye

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

animal organ morphogenesis

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

photoreceptor cell maintenance

IBA

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q2QI47

1 reference

Laminin G domain

1 reference

Laminin, N-terminal

1 reference

LamG-like jellyroll fold

1 reference

Laminin EGF domain

1 reference