GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization (Q22009030)

GOA release 2020-03-11

S H Shin

1

S H

Shin

1 reference

7 February 2023

P Kogerman

2

P

Kogerman

1 reference

7 February 2023

E Lindström

3

E

Lindström

1 reference

7 February 2023

R Toftgárd

4

R

Toftgárd

1 reference

7 February 2023

L G Biesecker

5

L G

Proceedings of the National Academy of Sciences of the United States of America

Biesecker

1 reference

7 February 2023

language of work or name

English

0 references

publication date

16 March 1999

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published in

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volume

96

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issue

6

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page(s)

2880-4

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cites work

Mutation in GLI3 in postaxial polydactyly type A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Axial (HNF3beta) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

12 September 2017

Pallister-Hall syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Identification of optimized target sequences for the GLI3 zinc finger protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

12 September 2017

Strike three for GLI3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Catching a Gli-mpse of Hedgehog

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Multigenic control of the localization of the zone of polarizing activity in limb morphogenesis in the mouse.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Extending the Pallister-Hall syndrome to include other central nervous system malformations

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

GLI activates transcription through a herpes simplex viral protein 16-like activation domain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Point mutations in human GLI3 cause Greig syndrome.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15863

Carboxy-terminally truncated Gli3 proteins associate with Smads

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10077605

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.6.2880

1 reference

5057529

ADS bibcode

1999PNAS...96.2880S

0 references

5057529

1 reference

1 reference

1 reference