Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells (Q22010574)

Cyclin E1

1 reference

NEDD8 ubiquitin like modifier

1 reference

protein neddylation

1 reference

Cyclin E1

1 reference

Neural precursor cell expressed, developmentally down-regulated gene 8

1 reference

Cullin 3

1 reference

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

protein ubiquitination

1 reference

J D Singer

1

J D

Singer

1 reference

7 February 2023

M Gurian-West

series ordinal

2

author given names

M

author last names

Gurian-West

1 reference

7 February 2023

B Clurman

series ordinal

3

author given names

B

author last names

Clurman

1 reference

7 February 2023

J M Roberts

series ordinal

4

author given names

J M

author last names

Roberts

1 reference

7 February 2023

language of work or name

English

0 references

publication date

15 September 1999

0 references

published in

Genes & Development

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volume

13

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issue

18

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page(s)

2375-87

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cites work

1 reference

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19 March 2017

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Cloning and expression analysis of a novel salicylate suppressible gene, Hs-CUL-3, a member of cullin/Cdc53 family

19 March 2017

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A new NEDD8-ligating system for cullin-4A

19 March 2017

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Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

19 March 2017

1 reference

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Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

19 March 2017

1 reference

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Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

19 March 2017

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Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

19 March 2017

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cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

19 March 2017

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Different roles for cyclins D1 and E in regulation of the G1-to-S transition

19 March 2017

1 reference

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

19 March 2017

1 reference

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The retinoblastoma protein and cell cycle control

19 March 2017

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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

19 March 2017

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

19 March 2017

1 reference

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A novel protein modification pathway related to the ubiquitin system

19 March 2017

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Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

19 March 2017

1 reference

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Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

19 March 2017

1 reference

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

19 March 2017

1 reference

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

19 March 2017

1 reference

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Identification of NEDD8-conjugation site in human cullin-2

19 March 2017

1 reference

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Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A

19 March 2017

1 reference

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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

19 March 2017

1 reference

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Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein

19 March 2017

1 reference

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Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

19 March 2017

1 reference

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Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

19 March 2017

1 reference

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Distinct roles for cyclin-dependent kinases in cell cycle control

7 April 2017

1 reference

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

7 April 2017

1 reference

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How the cyclin became a cyclin: regulated proteolysis in the cell cycle

7 April 2017

1 reference

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Substrate targeting in the ubiquitin system

12 September 2017

1 reference

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Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

12 September 2017

1 reference

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Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

12 September 2017

1 reference

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IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2.

12 September 2017

1 reference

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Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

12 September 2017

1 reference

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Reprogramming the cell cycle for endoreduplication in rodent trophoblast cells

12 September 2017

1 reference

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A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Regulation of cyclin E transcription by E2Fs and retinoblastoma protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Regulation of the cyclin E gene by transcription factor E2F1

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation

12 September 2017

1 reference

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Protein oligomerization in the endoplasmic reticulum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Fluctuations in cyclin E levels are required for multiple rounds of endocycle S phase in Drosophila.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Cyclin E-CDK2 is a regulator of p27Kip1.

30 May 2018

1 reference

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

30 May 2018

1 reference

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Cyclin-dependent regulation of G1 in mammalian fibroblasts.

30 May 2018

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Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains

30 May 2018

1 reference

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A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Cell cycle control of DNA replication by a homologue from human cells of the p34cdc2 protein kinase

30 May 2018

1 reference

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The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo

30 May 2018

1 reference

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Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

30 May 2018

1 reference

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Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317026

Association of human cyclin E with a periodic G1-S phase protein kinase

29 November 2018

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12 December 2020

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

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12 December 2020

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

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12 December 2020

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

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12 December 2020

S-Phase entry upon ectopic expression of G1 cyclin-dependent kinases in the absence of retinoblastoma protein phosphorylation

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12 December 2020

Identifiers

DOI

10.1101/GAD.13.18.2375

1 reference

3134714

3134714

1 reference

1 reference

1 reference