A novel cofactor for p300 that regulates the p53 response (Q22010639)

tumor protein p53

1 reference

positive regulation of DNA-binding transcription factor activity

1 reference

E1A binding protein p300

1 reference

Junction-mediating and regulatory protein

1 reference

N Shikama

1

N

Shikama

1 reference

7 February 2023

C W Lee

2

C W

Lee

1 reference

7 February 2023

S France

3

S

France

1 reference

7 February 2023

L Delavaine

4

L

Delavaine

1 reference

7 February 2023

J Lyon

5

J

Lyon

1 reference

7 February 2023

M Krstic-Demonacos

6

M

Krstic-Demonacos

1 reference

7 February 2023

N B La Thangue

7

N B

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

La Thangue

1 reference

7 February 2023

language of work or name

English

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publication date

September 1999

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published in

Molecular Cell

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volume

4

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issue

3

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page(s)

365-76

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cites work

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7 January 2021

Recruitment of p300/CBP in p53-dependent signal pathways

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The CBP co-activator is a histone acetyltransferase

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators

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7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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7 January 2021

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

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7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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7 January 2021

Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor

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7 January 2021

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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7 January 2021

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

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7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

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7 January 2021

A new component of the transcription factor DRTF1/E2F.

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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7 January 2021

Synergistic activation of transcription by CBP and p53

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7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Modes of DAPI banding and simultaneous in situ hybridization

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High-resolution mapping of mammalian genes by in situ hybridization to free chromatin

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Promoter specificity and stability control of the p53-related protein p73

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7 January 2021

Functional interplay between p53 and E2F through co-activator p300.

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7 January 2021

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

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7 January 2021

Binding and modulation of p53 by p300/CBP coactivators

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7 January 2021

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

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7 January 2021

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

The transcriptional coactivators p300 and CBP are histone acetyltransferases

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

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7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

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7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

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7 January 2021

The p300/CBP family: integrating signals with transcription factors and chromatin

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7 January 2021

Functional interaction between DP-1 and p53

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Loss of heterozygosity on chromosome 5q in ovarian cancer is frequently accompanied by TP53 mutation and identifies a tumour suppressor gene locus at 5q13.1-21.

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7 January 2021

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

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7 January 2021

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

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7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

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7 January 2021

Life, death, and the pursuit of apoptosis.

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Characterization of a hairy cell leukemia-associated 5q13.3 inversion breakpoint

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7 January 2021

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

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7 January 2021