Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 (Q22010683)

animal organ morphogenesis

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

S L Nutt

1

Stephen L.

Nutt

1 reference

6 February 2023

B Heavey

series ordinal

2

author given names

Barry

author last names

Heavey

1 reference

6 February 2023

A G Rolink

series ordinal

3

author given names

Antonius G.

author last names

Rolink

1 reference

6 February 2023

M Busslinger

series ordinal

4

author given names

Meinrad

author last names

Busslinger

1 reference

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

6 February 2023

language of work or name

English

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publication date

7 October 1999

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published in

Nature

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volume

401

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issue

6753

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page(s)

556-62

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cites work

1 reference

7 January 2021

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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7 January 2021

IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development

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7 January 2021

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

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7 January 2021

Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis

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7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

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7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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7 January 2021

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

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7 January 2021

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

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7 January 2021

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

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7 January 2021

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

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7 January 2021

Identification of the earliest B lineage stage in mouse bone marrow

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7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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7 January 2021

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

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7 January 2021

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

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7 January 2021

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

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7 January 2021

Dendritic cells and the control of immunity

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7 January 2021

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1 reference

7 January 2021

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

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7 January 2021

A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors

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7 January 2021

Development and tolerance of natural killer cells.

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7 January 2021

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

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7 January 2021

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

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7 January 2021

Bone and haematopoietic defects in mice lacking c-fos

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7 January 2021

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

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7 January 2021

Multilineage gene expression precedes commitment in the hemopoietic system

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7 January 2021

The B/macrophage cell: an elusive link between CD5+ B lymphocytes and macrophages

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7 January 2021

Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: involvement of common leukemic progenitors and their developmental abnormality of "lineage infidelity".

1 reference

7 January 2021

Hemopoietic lineage switch: v-raf oncogene converts Emu-myc transgenic B cells into macrophages

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7 January 2021

Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1.

1 reference

7 January 2021

Transformation of murine bone marrow cells with combined v-raf-v-myc oncogenes yields clonally related mature B cells and macrophages

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7 January 2021

Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes

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7 January 2021

Bipotential precursors of B cells and macrophages in murine fetal liver

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7 January 2021

Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver.

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7 January 2021

Identification of a fetal hematopoietic precursor with B cell, T cell, and macrophage potential

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7 January 2021

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

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7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 reference

7 January 2021

Loops, lineage, and leukemia

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7 January 2021

The B29 (immunoglobulin beta-chain) gene is a genetic target for early B-cell factor

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7 January 2021

Independent regulation of the two Pax5 alleles during B-cell development.

1 reference

7 January 2021

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

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7 January 2021

Identifiers

DOI

10.1038/44076

1 reference

Consolidated OpenCitations Corpus – April 2017

3339901

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3339901

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference